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Live data · NADAC + Part D CY24 · reviewed daily

Megestrol

Megestrol supplements progesterone activity, used in contraception and hormone therapy.

First FDA approval1995-11-30
Generic availableYes · 5 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$38.8M in CY2024 Part D spend707K claims · 282K beneficiaries · 329 plans surveyed

Lowest NADAC
$0.132/unit
12 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.274
Across all dosage forms in distribution.
Highest NADAC
$1.16
Wide spread — brand-strength NDCs still in market.
Plans with PA
545 / 329
Substantial PA friction across plans.

Questions a plan sponsor actually asks.

FAQPage schema10 entries indexed · 4 visible
What is Megestrol used for?

Megestrol supplements progesterone activity, used in contraception and hormone therapy.

Is there a generic for Megestrol?

Yes. 8 ANDAs filed at FDA, 5 generic manufacturers currently shipping.

How much does my plan pay for Megestrol?

Across 329 Part D plans, Megestrol averages $0.274/unit (NADAC). Lowest available: $0.132/unit. Highest in distribution: $1.16/unit.

Is Megestrol on the FDA shortage list?

No. Megestrol is not currently on the FDA Drug Shortage Database.

6 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Progestin6 alternatives in D1
01
Desogestrel and Ethinyl Estradiol
Brand: AVERI
$0.135Lowest NADAC
11Generic mfrs
CY24 Part D spend
Compare →
02
Desogestrel and Ethinyl Estradiol and Ethinyl Estradiol
Brand: SIMLIYA
$0.168Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Drospirenone and Ethinyl Estradiol
Brand: Jasmiel
$0.157Lowest NADAC
11Generic mfrs
CY24 Part D spend
Compare →
04
Ethynodiol Diacetate and Ethinyl Estradiol
Brand: Kelnor 1/35
$0.338Lowest NADAC
4Generic mfrs
CY24 Part D spend
Compare →
05
Etonogestrel
Brand: Nexplanon
Lowest NADAC
0Generic mfrs
$1.0MCY24 Part D spend
Compare →
06
Levonorgestrel
Brand: Kyleena
Lowest NADAC
0Generic mfrs
$1.4MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (8 approvals on file) · NADAC unit costs: CMS NADAC weekly file (12 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.