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Live data · NADAC + Part D CY24 · reviewed daily

Metaxalone

Muscle Relaxant class · 6 generic manufacturers · 7 ANDAs filed at FDA.

First FDA approval2013-05-31
Generic availableYes · 6 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$12.6M in CY2024 Part D spend108K claims · 47K beneficiaries · 329 plans surveyed

Lowest NADAC
$0.377/unit
16 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.670
Across all dosage forms in distribution.
Highest NADAC
$2.72
Wide spread — brand-strength NDCs still in market.
Plans with PA
34 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema9 entries indexed · 4 visible
What is Metaxalone used for?

Metaxalone is a Muscle Relaxant medication tracked in Medicare Part D.

Is there a generic for Metaxalone?

Yes. 7 ANDAs filed at FDA, 6 generic manufacturers currently shipping.

How much does my plan pay for Metaxalone?

Across 329 Part D plans, Metaxalone averages $0.670/unit (NADAC). Lowest available: $0.377/unit. Highest in distribution: $2.72/unit.

Is Metaxalone on the FDA shortage list?

No. Metaxalone is not currently on the FDA Drug Shortage Database.

5 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Muscle Relaxant5 alternatives in D1
01
Carisoprodol
Brand: Soma
$0.067Lowest NADAC
13Generic mfrs
$8.4MCY24 Part D spend
Compare →
02
Chlorzoxazone
Muscle Relaxant
$0.215Lowest NADAC
11Generic mfrs
$24.2MCY24 Part D spend
Compare →
03
Methocarbamol
Brand: ATMEKSI
$0.037Lowest NADAC
18Generic mfrs
$65.6MCY24 Part D spend
Compare →
04
Methocarbamol Tablets
Brand: Methocarbamol
$0.037Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
05
Orphenadrine
Muscle Relaxant
$0.458Lowest NADAC
7Generic mfrs
$3.5MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (8 approvals on file) · NADAC unit costs: CMS NADAC weekly file (16 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.