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Metoprolol and Hydrochlorothiazide

Metoprolol and Hydrochlorothiazide reduces fluid retention and lowers blood pressure by increasing urine output.

First FDA approval2004-08-20
Generic availableYes · 3 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$1.00/unit
7 NDCs benchmarked, lowest of all strengths.
Average NADAC
$1.13
Across all dosage forms in distribution.
Highest NADAC
$1.29
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema8 entries indexed · 4 visible
What is Metoprolol and Hydrochlorothiazide used for?

Metoprolol and Hydrochlorothiazide reduces fluid retention and lowers blood pressure by increasing urine output.

Is there a generic for Metoprolol and Hydrochlorothiazide?

Yes. 8 ANDAs filed at FDA, 3 generic manufacturers currently shipping.

How much does my plan pay for Metoprolol and Hydrochlorothiazide?

Across 329 Part D plans, Metoprolol and Hydrochlorothiazide averages $1.13/unit (NADAC). Lowest available: $1.00/unit. Highest in distribution: $1.29/unit.

Is Metoprolol and Hydrochlorothiazide on the FDA shortage list?

No. Metoprolol and Hydrochlorothiazide is not currently on the FDA Drug Shortage Database.

4 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Thiazide Diuretic6 alternatives in D1
01
Losartan and Hydrochlorothiazide
Brand: HYZAAR
$0.065Lowest NADAC
10Generic mfrs
CY24 Part D spend
Compare →
02
Hydrochlorothiazide
Brand: INZIRQO
$0.012Lowest NADAC
11Generic mfrs
$122.0MCY24 Part D spend
Compare →
03
Bisoprolol and Hydrochlorothiazide
Thiazide Diuretic
$0.195Lowest NADAC
8Generic mfrs
CY24 Part D spend
Compare →
04
Olmesartan Medoxomil and Hydrochlorothiazide
Thiazide Diuretic
$0.169Lowest NADAC
10Generic mfrs
CY24 Part D spend
Compare →
05
Valsartan and Hydrochlorothiazide
Brand: Diovan HCT
$0.124Lowest NADAC
7Generic mfrs
CY24 Part D spend
Compare →
06
Triamterene and Hydrochlorothiazide
Thiazide Diuretic
$0.096Lowest NADAC
8Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (9 approvals on file) · NADAC unit costs: CMS NADAC weekly file (7 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.