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Live data · NADAC + Part D CY24 · reviewed daily

Nafcillin (Nafcillin)

Nafcillin kills bacteria by disrupting cell wall synthesis.

First FDA approval1989-10-31
Generic availableYes · 5 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$4.0M in CY2024 Part D spend6K claims · 1K beneficiaries · 329 plans surveyed

Lowest NADAC
/unit
0 NDCs benchmarked, lowest of all strengths.
Average NADAC
Across all dosage forms in distribution.
Highest NADAC
Range is tight.
Plans with PA
86 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema9 entries indexed · 4 visible
What is Nafcillin used for?

Nafcillin kills bacteria by disrupting cell wall synthesis.

Is there a generic for Nafcillin?

Yes. 13 ANDAs filed at FDA, 5 generic manufacturers currently shipping.

How much does my plan pay for Nafcillin?

NADAC pricing data not currently available for this drug.

Is Nafcillin on the FDA shortage list?

No. Nafcillin is not currently on the FDA Drug Shortage Database.

5 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Penicillin-class Antibacterial6 alternatives in D1
01
Ampicillin
Brand: AMPICILLIN
$0.458Lowest NADAC
8Generic mfrs
$7.0MCY24 Part D spend
Compare →
02
Ampicillin and Sulbactam
Brand: Ampicillin and Sulbactam
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Oxacillin
Brand: Oxacillin
Lowest NADAC
5Generic mfrs
$3.2MCY24 Part D spend
Compare →
04
Penicillin G
Brand: PENICILLIN G POTASSIUM
Lowest NADAC
5Generic mfrs
$2.2MCY24 Part D spend
Compare →
05
Penicillin V
Penicillin-class Antibacterial
$0.044Lowest NADAC
4Generic mfrs
$4.2MCY24 Part D spend
Compare →
06
Piperacillin and Tazobactam
Brand: PIPERACILLIN AND TAZOBACTAM
$3.49Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.