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Live data · NADAC + Part D CY24 · reviewed daily

Nitrofurantoin and Macrocrystalline (Macrobid)

Nitrofuran Antibacterial class · 12 generic manufacturers · 23 ANDAs filed at FDA.

First FDA approval2011-05-25
Generic availableYes · 12 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$0.332/unit
2 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.332
Across all dosage forms in distribution.
Highest NADAC
$0.332
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema10 entries indexed · 4 visible
What is Nitrofurantoin and Macrocrystalline used for?

Nitrofurantoin and Macrocrystalline is a Nitrofuran Antibacterial medication tracked in Medicare Part D.

Is there a generic for Nitrofurantoin and Macrocrystalline?

Yes. 23 ANDAs filed at FDA, 12 generic manufacturers currently shipping.

How much does my plan pay for Nitrofurantoin and Macrocrystalline?

Across 329 Part D plans, Nitrofurantoin and Macrocrystalline averages $0.332/unit (NADAC). Lowest available: $0.332/unit. Highest in distribution: $0.332/unit.

Is Nitrofurantoin and Macrocrystalline on the FDA shortage list?

No. Nitrofurantoin and Macrocrystalline is not currently on the FDA Drug Shortage Database.

6 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Nitrofuran Antibacterial6 alternatives in D1
01
Nitrofurantion
Nitrofuran Antibacterial
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
02
Nitrofurantion Macrocrystals
Nitrofuran Antibacterial
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Nitrofurantoin
Nitrofuran Antibacterial
$0.142Lowest NADAC
9Generic mfrs
$9.8MCY24 Part D spend
Compare →
04
Nitrofurantoin (Macrocrystals)
Nitrofuran Antibacterial
$0.142Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
05
Nitrofurantoin (Monohydrate and Macrocrystals)
Brand: NITROFURANTOIN
$0.332Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
06
Nitrofurantoin Oral Suspension
Nitrofuran Antibacterial
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (2 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.