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Live data · NADAC + Part D CY24 · reviewed daily

Nystatin Ointment (Nystatin)

Polyene Antifungal class · 0 generic manufacturers · 0 ANDAs filed at FDA.

First FDA approval2017-10-06
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$0.248/unit
2 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.252
Across all dosage forms in distribution.
Highest NADAC
$0.257
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema9 entries indexed · 4 visible
What is Nystatin Ointment used for?

Nystatin Ointment is a Polyene Antifungal medication tracked in Medicare Part D.

Is there a generic for Nystatin Ointment?

No. Nystatin Ointment is brand-only with no generic equivalents currently in market.

How much does my plan pay for Nystatin Ointment?

Across 329 Part D plans, Nystatin Ointment averages $0.252/unit (NADAC). Lowest available: $0.248/unit. Highest in distribution: $0.257/unit.

Is Nystatin Ointment on the FDA shortage list?

No. Nystatin Ointment is not currently on the FDA Drug Shortage Database.

5 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Polyene Antifungal5 alternatives in D1
01
Nystatin
Brand: Mycostatin
$0.065Lowest NADAC
24Generic mfrs
$116.2MCY24 Part D spend
Compare →
02
Nystatin Cream
Brand: Nystatin
$0.155Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Nystatin Topical Powder
Brand: KLAYESTA
$0.275Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
04
Nystatin and Triamcinolone Acetonide
Polyene Antifungal
$0.208Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
05
Nystatin, Triamcinolone Acetonide
Brand: NYSTATIN AND TRIAMCINOLONE ACETONIDE
$0.208Lowest NADAC
13Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book · NADAC unit costs: CMS NADAC weekly file (2 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.