Live data · NADAC + Part D CY24 · reviewed daily

Orphenadrine

First FDA approval1998-06-19
Generic availableYes · 7 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$3.5M in CY2024 Part D spend108K claims · 67K beneficiaries · 329 plans surveyed

Lowest NADAC
$0.454/unit
6 NDCs benchmarked, lowest of all strengths.
Average NADAC
$3.32
Across all dosage forms in distribution.
Highest NADAC
$7.07
Wide spread — brand-strength NDCs still in market.
Plans with PA
25 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema8 entries indexed · 4 visible
What is Orphenadrine used for?

Orphenadrine is tracked in Medicare Part D. Specific indication information is not available in our current dataset.

Sources: CMS Part D Spending CY24 · CMS NADAC weekly · FDA Orange Book
Is there a generic for Orphenadrine?

Yes. 8 ANDAs filed at FDA, 7 generic manufacturers currently shipping.

Sources: CMS Part D Spending CY24 · CMS NADAC weekly · FDA Orange Book
How much does my plan pay for Orphenadrine?

Across 329 Part D plans, Orphenadrine averages $3.32/unit (NADAC). Lowest available: $0.454/unit. Highest in distribution: $7.07/unit.

Sources: CMS Part D Spending CY24 · CMS NADAC weekly · FDA Orange Book
Is Orphenadrine on the FDA shortage list?

No. Orphenadrine is not currently on the FDA Drug Shortage Database.

Sources: CMS Part D Spending CY24 · CMS NADAC weekly · FDA Orange Book

4 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Related questions.

Q&A librarySourced · reviewed quarterly
pricingWhat is NADAC?pricingIs NADAC the same as my PBM cost?pricingWhat is spread pricing?pricingWhat is a NADAC pass-through PBM contract?pricingWhat's the difference between AWP, MAC, and NADAC?pricingWhat is a dispensing fee in a PBM contract?
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Sources · every number above traces back.

Last refresh15 Oct 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (8 approvals on file) · NADAC unit costs: CMS NADAC weekly file (6 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.