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Live data · NADAC + Part D CY24 · reviewed daily

Oxaprozin (COXANTO)

Oxaprozin reduces pain, inflammation, and fever by inhibiting prostaglandin synthesis.

First FDA approval1992-10-29
Generic availableYes · 4 mfrs
Shortage statusDiscontinued
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$1.7M in CY2024 Part D spend23K claims · 8K beneficiaries · 329 plans surveyed

Lowest NADAC
$0.595/unit
5 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.595
Across all dosage forms in distribution.
Highest NADAC
$0.595
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Oxaprozin used for?

Oxaprozin reduces pain, inflammation, and fever by inhibiting prostaglandin synthesis.

Is there a generic for Oxaprozin?

Yes. 4 ANDAs filed at FDA, 4 generic manufacturers currently shipping.

How much does my plan pay for Oxaprozin?

Across 329 Part D plans, Oxaprozin averages $0.595/unit (NADAC). Lowest available: $0.595/unit. Highest in distribution: $0.595/unit.

Is Oxaprozin on the FDA shortage list?

Oxaprozin has been discontinued by its manufacturer(s).

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Nonsteroidal Anti-inflammatory Drug6 alternatives in D1
01
Diclofenac
Brand: Cambia
$0.069Lowest NADAC
41Generic mfrs
$610.4MCY24 Part D spend
Compare →
02
Celecoxib
Brand: CELEBREX
$0.071Lowest NADAC
18Generic mfrs
$257.9MCY24 Part D spend
Compare →
03
Ibuprofen
Brand: Caldolor
$0.024Lowest NADAC
13Generic mfrs
$75.6MCY24 Part D spend
Compare →
04
Naproxen
Brand: EC-NAPROXEN
$0.046Lowest NADAC
17Generic mfrs
$57.0MCY24 Part D spend
Compare →
05
Meloxicam
Brand: QAMZOVA
$0.016Lowest NADAC
13Generic mfrs
$82.8MCY24 Part D spend
Compare →
06
Etodolac
Nonsteroidal Anti-inflammatory Drug
$0.253Lowest NADAC
11Generic mfrs
$15.9MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (6 approvals on file) · NADAC unit costs: CMS NADAC weekly file (5 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.