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Live data · NADAC + Part D CY24 · reviewed daily

Paliperidone (INVEGA)

Paliperidone treats schizophrenia, bipolar disorder, and related conditions by modulating dopamine and serotonin receptors.

First FDA approval2006-12-19
Generic availableYes · 11 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$119.1M in CY2024 Part D spend602K claims · 96K beneficiaries · 329 plans surveyed

Lowest NADAC
$0.978/unit
20 NDCs benchmarked, lowest of all strengths.
Average NADAC
$1.01
Across all dosage forms in distribution.
Highest NADAC
$1.04
Range is tight.
Plans with PA
653 / 329
Substantial PA friction across plans.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Paliperidone used for?

Paliperidone treats schizophrenia, bipolar disorder, and related conditions by modulating dopamine and serotonin receptors.

Is there a generic for Paliperidone?

Yes. 39 ANDAs filed at FDA, 11 generic manufacturers currently shipping.

How much does my plan pay for Paliperidone?

Across 329 Part D plans, Paliperidone averages $1.01/unit (NADAC). Lowest available: $0.978/unit. Highest in distribution: $1.04/unit.

Is Paliperidone on the FDA shortage list?

No. Paliperidone is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Atypical Antipsychotic6 alternatives in D1
01
Aripiprazole
Brand: ABILIFY
$0.098Lowest NADAC
22Generic mfrs
$1.45BCY24 Part D spend
Compare →
02
Aripiprazole Oral
Brand: Aripiprazole
$0.320Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Aripiprazole Orally Disintegrating
Brand: Aripiprazole
$2.87Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
04
Asenapine
Brand: Asenapine
$2.23Lowest NADAC
3Generic mfrs
$44.6MCY24 Part D spend
Compare →
05
Brexpiprazole
Brand: Rexulti
$49.50Lowest NADAC
1Generic mfrs
$1.37BCY24 Part D spend
Compare →
06
Cariprazine
Brand: Vraylar
$50.91Lowest NADAC
0Generic mfrs
$1.75BCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (20 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.