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Live data · NADAC + Part D CY24 · reviewed daily

Penicillin G (PENICILLIN G POTASSIUM)

Penicillin G kills bacteria by disrupting cell wall synthesis.

First FDA approval1990-06-25
Generic availableYes · 5 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$2.2M in CY2024 Part D spend7K claims · 2K beneficiaries · 329 plans surveyed

Lowest NADAC
/unit
0 NDCs benchmarked, lowest of all strengths.
Average NADAC
Across all dosage forms in distribution.
Highest NADAC
Range is tight.
Plans with PA
64 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Penicillin G used for?

Penicillin G kills bacteria by disrupting cell wall synthesis.

Is there a generic for Penicillin G?

Yes. 12 ANDAs filed at FDA, 5 generic manufacturers currently shipping.

How much does my plan pay for Penicillin G?

NADAC pricing data not currently available for this drug.

Is Penicillin G on the FDA shortage list?

No. Penicillin G is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Penicillin-class Antibacterial6 alternatives in D1
01
Ampicillin
Brand: AMPICILLIN
$0.458Lowest NADAC
8Generic mfrs
$7.0MCY24 Part D spend
Compare →
02
Ampicillin and Sulbactam
Brand: Ampicillin and Sulbactam
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Nafcillin
Brand: Nafcillin
Lowest NADAC
5Generic mfrs
$4.0MCY24 Part D spend
Compare →
04
Oxacillin
Brand: Oxacillin
Lowest NADAC
5Generic mfrs
$3.2MCY24 Part D spend
Compare →
05
Penicillin V
Penicillin-class Antibacterial
$0.044Lowest NADAC
4Generic mfrs
$4.2MCY24 Part D spend
Compare →
06
Piperacillin and Tazobactam
Brand: PIPERACILLIN AND TAZOBACTAM
$3.49Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.