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Live data · NADAC + Part D CY24 · reviewed daily

Pioglitazone (Actos)

Peroxisome Proliferator Receptor alpha Agonist class · 11 generic manufacturers · 33 ANDAs filed at FDA.

First FDA approval1999-07-15
Generic availableYes · 11 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$65.9M in CY2024 Part D spend4.9M claims · 1.6M beneficiaries · 329 plans surveyed

Lowest NADAC
$0.069/unit
20 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.069
Across all dosage forms in distribution.
Highest NADAC
$0.069
Range is tight.
Plans with PA
3 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Pioglitazone used for?

Pioglitazone is a Peroxisome Proliferator Receptor alpha Agonist medication tracked in Medicare Part D.

Is there a generic for Pioglitazone?

Yes. 33 ANDAs filed at FDA, 11 generic manufacturers currently shipping.

How much does my plan pay for Pioglitazone?

Across 329 Part D plans, Pioglitazone averages $0.069/unit (NADAC). Lowest available: $0.069/unit. Highest in distribution: $0.069/unit.

Is Pioglitazone on the FDA shortage list?

No. Pioglitazone is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Peroxisome Proliferator Receptor alpha Agonist3 alternatives in D1
01
Fenofibrate
Brand: ANTARA
$0.079Lowest NADAC
26Generic mfrs
$89.1MCY24 Part D spend
Compare →
02
Fenofibric Acid
Peroxisome Proliferator Receptor alpha Agonist
$0.153Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Gemfibrozil
Brand: Lopid
$0.103Lowest NADAC
8Generic mfrs
$21.1MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (20 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.