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Live data · NADAC + Part D CY24 · reviewed daily

Plecanatide (Trulance)

Guanylate Cyclase-C Agonist class · 0 generic manufacturers · 0 ANDAs filed at FDA.

First FDA approval2017-02-21
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$183.4M in CY2024 Part D spend229K claims · 75K beneficiaries · 329 plans surveyed

Lowest NADAC
/unit
0 NDCs benchmarked, lowest of all strengths.
Average NADAC
Across all dosage forms in distribution.
Highest NADAC
Range is tight.
Plans with PA
1 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema12 entries indexed · 4 visible
What is Plecanatide used for?

Plecanatide is a Guanylate Cyclase-C Agonist medication tracked in Medicare Part D.

Is there a generic for Plecanatide?

No. Plecanatide is brand-only with no generic equivalents currently in market.

How much does my plan pay for Plecanatide?

NADAC pricing data not currently available for this drug.

Is Plecanatide on the FDA shortage list?

No. Plecanatide is not currently on the FDA Drug Shortage Database.

8 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Guanylate Cyclase-C Agonist1 alternative in D1
01
Linaclotide
Brand: Linzess
$9.02Lowest NADAC
0Generic mfrs
$3.07BCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (1 approvals on file) · NADAC unit costs: CMS NADAC weekly file · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.