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Live data · NADAC + Part D CY24 · reviewed daily

Promethazine and Codeine

First FDA approval2018-03-12
Generic availableYes · 5 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$0.050/unit
3 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.050
Across all dosage forms in distribution.
Highest NADAC
$0.050
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema6 entries indexed · 4 visible
What is Promethazine and Codeine used for?

Promethazine and Codeine is a this drug class medication tracked in Medicare Part D.

Is there a generic for Promethazine and Codeine?

Yes. 5 ANDAs filed at FDA, 5 generic manufacturers currently shipping.

How much does my plan pay for Promethazine and Codeine?

Across 329 Part D plans, Promethazine and Codeine averages $0.050/unit (NADAC). Lowest available: $0.050/unit. Highest in distribution: $0.050/unit.

Is Promethazine and Codeine on the FDA shortage list?

No. Promethazine and Codeine is not currently on the FDA Drug Shortage Database.

2 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (5 approvals on file) · NADAC unit costs: CMS NADAC weekly file (3 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.