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Live data · NADAC + Part D CY24 · reviewed daily

Relugolix, Estradiol Hemihydrate, and Norethindrone (Myfembree)

Gonadotropin Releasing Hormone Receptor Antagonist class · 0 generic manufacturers · 0 ANDAs filed at FDA.

First FDA approval2021-05-26
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$45.36/unit
1 NDCs benchmarked, lowest of all strengths.
Average NADAC
$45.36
Across all dosage forms in distribution.
Highest NADAC
$45.36
Range is tight.
Plans with PA
40 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema9 entries indexed · 4 visible
What is Relugolix, Estradiol Hemihydrate, and Norethindrone used for?

Relugolix, Estradiol Hemihydrate, and Norethindrone is a Gonadotropin Releasing Hormone Receptor Antagonist medication tracked in Medicare Part D.

Is there a generic for Relugolix, Estradiol Hemihydrate, and Norethindrone?

No. Relugolix, Estradiol Hemihydrate, and Norethindrone is brand-only with no generic equivalents currently in market.

How much does my plan pay for Relugolix, Estradiol Hemihydrate, and Norethindrone?

Across 329 Part D plans, Relugolix, Estradiol Hemihydrate, and Norethindrone averages $45.36/unit (NADAC). Lowest available: $45.36/unit. Highest in distribution: $45.36/unit.

Is Relugolix, Estradiol Hemihydrate, and Norethindrone on the FDA shortage list?

No. Relugolix, Estradiol Hemihydrate, and Norethindrone is not currently on the FDA Drug Shortage Database.

5 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Gonadotropin Releasing Hormone Receptor Antagonist3 alternatives in D1
01
Cetrorelix
Brand: Cetrorelix
Lowest NADAC
5Generic mfrs
CY24 Part D spend
Compare →
02
Ganirelix
Brand: Fyremadel
$62.35Lowest NADAC
7Generic mfrs
CY24 Part D spend
Compare →
03
Relugolix
Brand: Orgovyx
Lowest NADAC
0Generic mfrs
$923.5MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book · NADAC unit costs: CMS NADAC weekly file (1 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.