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Live data · NADAC + Part D CY24 · reviewed daily

Rifapentine (Priftin)

Rifamycin Antimycobacterial class · 0 generic manufacturers · 0 ANDAs filed at FDA.

First FDA approval2017-02-08
Generic availableNo (brand-only)
Shortage statusActive shortage
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$818,510 in CY2024 Part D spend4K claims · 3K beneficiaries · 329 plans surveyed

Lowest NADAC
$4.85/unit
1 NDCs benchmarked, lowest of all strengths.
Average NADAC
$4.85
Across all dosage forms in distribution.
Highest NADAC
$4.85
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Rifapentine used for?

Rifapentine is a Rifamycin Antimycobacterial medication tracked in Medicare Part D.

Is there a generic for Rifapentine?

No. Rifapentine is brand-only with no generic equivalents currently in market.

How much does my plan pay for Rifapentine?

Across 329 Part D plans, Rifapentine averages $4.85/unit (NADAC). Lowest available: $4.85/unit. Highest in distribution: $4.85/unit.

Is Rifapentine on the FDA shortage list?

Yes. Rifapentine is currently listed as an active FDA shortage.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Rifamycin Antimycobacterial2 alternatives in D1
01
Omeprazole Magnesium, Amoxicillin and Rifabutin
Brand: Talicia
$4.86Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
02
Rifabutin
Rifamycin Antimycobacterial
$9.18Lowest NADAC
1Generic mfrs
$10.4MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (1 approvals on file) · NADAC unit costs: CMS NADAC weekly file (1 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.