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Live data · NADAC + Part D CY24 · reviewed daily

Risankizumab-Rzaa (Skyrizi)

SKYRIZI is an interleukin-23 antagonist indicated for the treatment of: moderate-to-severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy. ( 1.1 ) active psoriat....

First FDA approval2021-04-26
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$4.58B in CY2024 Part D spend218K claims · 84K beneficiaries · 329 plans surveyed

Lowest NADAC
$9679.49/unit
3 NDCs benchmarked, lowest of all strengths.
Average NADAC
$18476.52
Across all dosage forms in distribution.
Highest NADAC
$22942.37
Range is tight.
Plans with PA
1212 / 329
Substantial PA friction across plans.

Questions a plan sponsor actually asks.

FAQPage schema10 entries indexed · 4 visible
What is Risankizumab-Rzaa used for?

SKYRIZI is an interleukin-23 antagonist indicated for the treatment of: moderate-to-severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy. ( 1.1 ) active psoriat....

Is there a generic for Risankizumab-Rzaa?

No. Risankizumab-Rzaa is brand-only with no generic equivalents currently in market.

How much does my plan pay for Risankizumab-Rzaa?

Across 329 Part D plans, Risankizumab-Rzaa averages $18476.52/unit (NADAC). Lowest available: $9679.49/unit. Highest in distribution: $22942.37/unit.

Is Risankizumab-Rzaa on the FDA shortage list?

No. Risankizumab-Rzaa is not currently on the FDA Drug Shortage Database.

6 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Interleukin-23 Antagonist3 alternatives in D1
01
Guselkumab
Brand: TREMFYA
$7349.67Lowest NADAC
0Generic mfrs
$1.13BCY24 Part D spend
Compare →
02
Mirikizumab-Mrkz
Brand: Omvoh
Lowest NADAC
0Generic mfrs
$11.0MCY24 Part D spend
Compare →
03
Tildrakizumab-Asmn
Brand: ILUMYA
Lowest NADAC
0Generic mfrs
$57.1MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book · NADAC unit costs: CMS NADAC weekly file (3 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.