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Live data · NADAC + Part D CY24 · reviewed daily

Ruxolitinib (JAKAFI)

Ruxolitinib targets specific kinase enzymes involved in cancer cell growth and proliferation.

First FDA approval2011-11-16
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$3.38B in CY2024 Part D spend280K claims · 62K beneficiaries · 329 plans surveyed

Lowest NADAC
$34.14/unit
1 NDCs benchmarked, lowest of all strengths.
Average NADAC
$34.14
Across all dosage forms in distribution.
Highest NADAC
$34.14
Range is tight.
Plans with PA
1642 / 329
Substantial PA friction across plans.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Ruxolitinib used for?

Ruxolitinib targets specific kinase enzymes involved in cancer cell growth and proliferation.

Is there a generic for Ruxolitinib?

No. Ruxolitinib is brand-only with no generic equivalents currently in market.

How much does my plan pay for Ruxolitinib?

Across 329 Part D plans, Ruxolitinib averages $34.14/unit (NADAC). Lowest available: $34.14/unit. Highest in distribution: $34.14/unit.

Is Ruxolitinib on the FDA shortage list?

No. Ruxolitinib is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Kinase Inhibitor6 alternatives in D1
01
Everolimus
Brand: Afinitor
$2.29Lowest NADAC
10Generic mfrs
$259.1MCY24 Part D spend
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02
Imatinib
Brand: Gleevec
$0.827Lowest NADAC
12Generic mfrs
$318.0MCY24 Part D spend
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03
Dasatinib
Brand: PHYRAGO
$29.19Lowest NADAC
8Generic mfrs
$850.6MCY24 Part D spend
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04
Everolimus Tablets
Brand: Everolimus
$2.29Lowest NADAC
0Generic mfrs
CY24 Part D spend
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05
Sunitinib Malate
Brand: SUTENT
Lowest NADAC
8Generic mfrs
$69.0MCY24 Part D spend
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06
Erlotinib
Brand: Erlotinib
Lowest NADAC
8Generic mfrs
$9.9MCY24 Part D spend
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Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (6 approvals on file) · NADAC unit costs: CMS NADAC weekly file (1 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.