Sacubitril and Valsartan (ENTRESTO)
Sacubitril and Valsartan lowers blood pressure by blocking angiotensin II receptors, used for hypertension and kidney protection.
Questions a plan sponsor actually asks.
What is Sacubitril and Valsartan used for?
Sacubitril and Valsartan lowers blood pressure by blocking angiotensin II receptors, used for hypertension and kidney protection.
Is there a generic for Sacubitril and Valsartan?
Yes. 42 ANDAs filed at FDA, 14 generic manufacturers currently shipping.
How much does my plan pay for Sacubitril and Valsartan?
Across 329 Part D plans, Sacubitril and Valsartan averages $0.531/unit (NADAC). Lowest available: $0.531/unit. Highest in distribution: $0.531/unit.
Is Sacubitril and Valsartan on the FDA shortage list?
No. Sacubitril and Valsartan is not currently on the FDA Drug Shortage Database.
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Same class. Different math.
Sources · every number above traces back.
Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (20 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.