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Live data · NADAC + Part D CY24 · reviewed daily

Spesolimab-Sbzo (SPEVIGO)

Interleukin-36 Receptor Antagonist class · 0 generic manufacturers · 0 ANDAs filed at FDA.

First FDA approval2022-09-01
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$12.1M in CY2024 Part D spend490 claims · 140 beneficiaries · 329 plans surveyed

Lowest NADAC
/unit
0 NDCs benchmarked, lowest of all strengths.
Average NADAC
Across all dosage forms in distribution.
Highest NADAC
Range is tight.
Plans with PA
56 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema10 entries indexed · 4 visible
What is Spesolimab-Sbzo used for?

Spesolimab-Sbzo is a Interleukin-36 Receptor Antagonist medication tracked in Medicare Part D.

Is there a generic for Spesolimab-Sbzo?

No. Spesolimab-Sbzo is brand-only with no generic equivalents currently in market.

How much does my plan pay for Spesolimab-Sbzo?

NADAC pricing data not currently available for this drug.

Is Spesolimab-Sbzo on the FDA shortage list?

No. Spesolimab-Sbzo is not currently on the FDA Drug Shortage Database.

6 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Interleukin-36 Receptor Antagonist1 alternative in D1
01
Spesolimab
Brand: SPEVIGO
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book · NADAC unit costs: CMS NADAC weekly file · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.