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Live data · NADAC + Part D CY24 · reviewed daily

Sulfamethoxazole and Trimethoprim (Bactrim)

Sulfonamide Antimicrobial class · 0 generic manufacturers · 0 ANDAs filed at FDA.

First FDA approval1983-07-01
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$0.039/unit
20 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.042
Across all dosage forms in distribution.
Highest NADAC
$0.047
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema9 entries indexed · 4 visible
What is Sulfamethoxazole and Trimethoprim used for?

Sulfamethoxazole and Trimethoprim is a Sulfonamide Antimicrobial medication tracked in Medicare Part D.

Is there a generic for Sulfamethoxazole and Trimethoprim?

No. Sulfamethoxazole and Trimethoprim is brand-only with no generic equivalents currently in market.

How much does my plan pay for Sulfamethoxazole and Trimethoprim?

Across 329 Part D plans, Sulfamethoxazole and Trimethoprim averages $0.042/unit (NADAC). Lowest available: $0.039/unit. Highest in distribution: $0.047/unit.

Is Sulfamethoxazole and Trimethoprim on the FDA shortage list?

No. Sulfamethoxazole and Trimethoprim is not currently on the FDA Drug Shortage Database.

5 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Sulfonamide Antimicrobial2 alternatives in D1
01
Sulfameth and Trimeth-Ds
Sulfonamide Antimicrobial
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
02
Sulfamethoxazole, Trimethoprim
Brand: Sulfamethox-TMP DS
Lowest NADAC
12Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book · NADAC unit costs: CMS NADAC weekly file (20 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.