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Live data · NADAC + Part D CY24 · reviewed daily

Tezacaftor and Ivacaftor (SYMDEKO)

First FDA approval2018-02-12
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
/unit
0 NDCs benchmarked, lowest of all strengths.
Average NADAC
Across all dosage forms in distribution.
Highest NADAC
Range is tight.
Plans with PA
308 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema8 entries indexed · 4 visible
What is Tezacaftor and Ivacaftor used for?

Tezacaftor and Ivacaftor is a this drug class medication tracked in Medicare Part D.

Is there a generic for Tezacaftor and Ivacaftor?

No. Tezacaftor and Ivacaftor is brand-only with no generic equivalents currently in market.

How much does my plan pay for Tezacaftor and Ivacaftor?

NADAC pricing data not currently available for this drug.

Is Tezacaftor and Ivacaftor on the FDA shortage list?

No. Tezacaftor and Ivacaftor is not currently on the FDA Drug Shortage Database.

4 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (2 approvals on file) · NADAC unit costs: CMS NADAC weekly file · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.