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Live data · NADAC + Part D CY24 · reviewed daily

Trifarotene (AKLIEF)

Trifarotene regulates cell growth and differentiation, used in dermatology and certain cancers.

First FDA approval2019-10-04
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$377,909 in CY2024 Part D spend529 claims · 293 beneficiaries · 329 plans surveyed

Lowest NADAC
$16.34/unit
1 NDCs benchmarked, lowest of all strengths.
Average NADAC
$16.34
Across all dosage forms in distribution.
Highest NADAC
$16.34
Range is tight.
Plans with PA
1 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Trifarotene used for?

Trifarotene regulates cell growth and differentiation, used in dermatology and certain cancers.

Is there a generic for Trifarotene?

No. Trifarotene is brand-only with no generic equivalents currently in market.

How much does my plan pay for Trifarotene?

Across 329 Part D plans, Trifarotene averages $16.34/unit (NADAC). Lowest available: $16.34/unit. Highest in distribution: $16.34/unit.

Is Trifarotene on the FDA shortage list?

No. Trifarotene is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Retinoid6 alternatives in D1
01
Acitretin
Retinoid
$2.20Lowest NADAC
6Generic mfrs
$20.7MCY24 Part D spend
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02
Adapalene
Brand: DIFFERIN
$0.495Lowest NADAC
6Generic mfrs
$4.9MCY24 Part D spend
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03
Adapalene Gel Usp,
Retinoid
$0.495Lowest NADAC
0Generic mfrs
CY24 Part D spend
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04
Adapalene and Benzoyl Peroxide
Brand: EPIDUO
$0.285Lowest NADAC
7Generic mfrs
CY24 Part D spend
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05
Adapalene and Benzoyl Peroxide Gel,
Retinoid
$0.285Lowest NADAC
0Generic mfrs
CY24 Part D spend
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06
Adapalene and Benzoyl Peroxide Topical
Brand: ADAPALENE AND BENZOYL PEROXIDE
$0.626Lowest NADAC
0Generic mfrs
CY24 Part D spend
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Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (1 approvals on file) · NADAC unit costs: CMS NADAC weekly file (1 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.