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Live data · NADAC + Part D CY24 · reviewed daily

Valacyclovir (VALTREX)

Valacyclovir hydrochloride is a deoxynucleoside analogue DNA polymerase inhibitor indicated for: Adult Patients ( 1.1 ) Cold Sores (Herpes Labialis) Genital Herpes Treatment in immunocompetent pati....

First FDA approval1995-08-01
Generic availableYes · 9 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$171.9M in CY2024 Part D spend5.1M claims · 2.6M beneficiaries · 329 plans surveyed

Lowest NADAC
$0.230/unit
20 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.230
Across all dosage forms in distribution.
Highest NADAC
$0.230
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Valacyclovir used for?

Valacyclovir hydrochloride is a deoxynucleoside analogue DNA polymerase inhibitor indicated for: Adult Patients ( 1.1 ) Cold Sores (Herpes Labialis) Genital Herpes Treatment in immunocompetent pati....

Is there a generic for Valacyclovir?

Yes. 18 ANDAs filed at FDA, 9 generic manufacturers currently shipping.

How much does my plan pay for Valacyclovir?

Across 329 Part D plans, Valacyclovir averages $0.230/unit (NADAC). Lowest available: $0.230/unit. Highest in distribution: $0.230/unit.

Is Valacyclovir on the FDA shortage list?

No. Valacyclovir is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor1 alternative in D1
01
Penciclovir
Brand: Denavir
$64.73Lowest NADAC
4Generic mfrs
$5.5MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (20 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.