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Live data · NADAC + Part D CY24 · reviewed daily

Zidovudine (RETROVIR)

Zidovudine blocks HIV replication by inhibiting reverse transcriptase.

First FDA approval2005-09-19
Generic availableYes · 4 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$250,683 in CY2024 Part D spend4K claims · 706 beneficiaries · 329 plans surveyed

Lowest NADAC
$0.150/unit
2 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.291
Across all dosage forms in distribution.
Highest NADAC
$0.432
Range is tight.
Plans with PA
0 / 329
Zero PA friction — switching is purely formulary.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Zidovudine used for?

Zidovudine blocks HIV replication by inhibiting reverse transcriptase.

Is there a generic for Zidovudine?

Yes. 7 ANDAs filed at FDA, 4 generic manufacturers currently shipping.

How much does my plan pay for Zidovudine?

Across 329 Part D plans, Zidovudine averages $0.291/unit (NADAC). Lowest available: $0.150/unit. Highest in distribution: $0.432/unit.

Is Zidovudine on the FDA shortage list?

No. Zidovudine is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor6 alternatives in D1
01
Abacavir
Brand: Abacavir
$0.652Lowest NADAC
5Generic mfrs
$4.2MCY24 Part D spend
Compare →
02
Bictegravir Sodium, Emtricitabine, and Tenofovir Alafenamide
Brand: Biktarvy
$136.73Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
03
Emtricitabine
Brand: Emtriva
$14.51Lowest NADAC
2Generic mfrs
$3.0MCY24 Part D spend
Compare →
04
Emtricitabine and Tdf
Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor
Lowest NADAC
0Generic mfrs
CY24 Part D spend
Compare →
05
Emtricitabine and Tenofovir Alafenamide
Brand: DESCOVY
$71.41Lowest NADAC
1Generic mfrs
CY24 Part D spend
Compare →
06
Emtricitabine and Tenofovir Disoproxil
Brand: Truvada
$0.457Lowest NADAC
10Generic mfrs
CY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (2 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.