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Live data · NADAC + Part D CY24 · reviewed daily

Zilucoplan (ZILBRYSQ)

Zilucoplan blocks complement system activation to treat rare blood and immune disorders.

First FDA approval2024-01-03
Generic availableNo (brand-only)
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$90.6M in CY2024 Part D spend2K claims · 483 beneficiaries · 329 plans surveyed

Lowest NADAC
/unit
0 NDCs benchmarked, lowest of all strengths.
Average NADAC
Across all dosage forms in distribution.
Highest NADAC
Range is tight.
Plans with PA
80 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Zilucoplan used for?

Zilucoplan blocks complement system activation to treat rare blood and immune disorders.

Is there a generic for Zilucoplan?

No. Zilucoplan is brand-only with no generic equivalents currently in market.

How much does my plan pay for Zilucoplan?

NADAC pricing data not currently available for this drug.

Is Zilucoplan on the FDA shortage list?

No. Zilucoplan is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Complement Inhibitor6 alternatives in D1
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Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (3 approvals on file) · NADAC unit costs: CMS NADAC weekly file · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.