Drug class profile · refreshed daily from federal data

Janus Kinase Inhibitor

4 molecules in this class, $2.49B combined CY2024 Part D spend across 347K claims. Class-level guide below for benefits decision-makers: where the money lives, where the savings live.

Last updated 14 Jul 2026

NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annualOrange Book: weeklyShortages: daily

Class summary at a glance.

Every drug in the Janus Kinase Inhibitor class tracked across NADAC, Part D Formulary, Part D Spending, FDA Orange Book, and shortage data. Ranked below by CY24 Part D spend. Click any molecule for the full drug profile.

Molecules in class: 4tracked in Part D
CY24 Part D spend: $2.49Bcombined across class
Total Rx claims: 347K67K unique beneficiaries
Generic mfrs (active): 1across all molecules

Every drug in this class, ranked by Part D spend.

CY2024 dataCMS Part D Spending Dashboard

Upadacitinib

Brand: Rinvoq · 327K Part D claims (CY24) · 63K beneficiaries · First FDA approval: 2019-08-16

Brand-only (no generics) 1217 plans require PA

Low NADAC$228.77

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Avg plan cost$305.41

Part D spend $2.41B 1× spread, current vs floor

Class share

97%

of class CY24 spend

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Baricitinib

Brand: Olumiant · 15K Part D claims (CY24) · 3K beneficiaries · First FDA approval: 2018-05-31

1 generic mfrs 98 plans require PA

Low NADAC$92.26

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Avg plan cost$138.46

Part D spend $56.8M 2× spread, current vs floor

Class share

of class CY24 spend

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Abrocitinib

Brand: CIBINQO · 5K Part D claims (CY24) · 1K beneficiaries · First FDA approval: 2022-02-24

Brand-only (no generics) 85 plans require PA

Low NADAC$196.57

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Avg plan cost$196.57

Part D spend $29.9M 1× spread, current vs floor

Class share

of class CY24 spend

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Delgocitinib

Brand: Anzupgo · — Part D claims (CY24) · First FDA approval: 2025-07-24

Brand-only (no generics) 12 plans require PA

Low NADAC—

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Avg plan cost—

Part D spend —

Class share

of class CY24 spend

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Class summary at a glance.

Every drug in this class, ranked by Part D spend.

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