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Drug class profile · refreshed daily from federal data

Selective Serotonin Reuptake Inhibitor (SSRI)

4 molecules in this class, $334.8M combined CY2024 Part D spend across 29.6M claims. Class-level guide below for benefits decision-makers: where the money lives, where the savings live.

Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annualOrange Book: weeklyShortages: daily

Class summary at a glance.

Every drug in the Selective Serotonin Reuptake Inhibitor (SSRI) class tracked across NADAC, Part D Formulary, Part D Spending, FDA Orange Book, and shortage data. Ranked below by CY24 Part D spend. Click any molecule for the full drug profile.

Molecules in class
4tracked in Part D
CY24 Part D spend
$334.8Mcombined across class
Total Rx claims
29.6M7.4M unique beneficiaries
Generic mfrs (active)
34across all molecules

Every drug in this class, ranked by Part D spend.

CY2024 dataCMS Part D Spending Dashboard
01
Sertraline
Brand: Zoloft · 24.4M Part D claims (CY24) · 6.0M beneficiaries · First FDA approval:
18 generic mfrs 0 plans require PA
Low NADAC$0.032
Avg plan cost$1.27
Part D spend $247.4M 40× spread, current vs floor
Class share
74%
of class CY24 spend
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02
Paroxetine
Brand: BRISDELLE · 5.2M Part D claims (CY24) · 1.3M beneficiaries · First FDA approval:
2 generic mfrs 686 plans require PA
Low NADAC$0.066
Avg plan cost$0.356
Part D spend $87.4M spread, current vs floor
Class share
26%
of class CY24 spend
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03
Citalopram
Brand: CITALOPRAM HYDROBROMIDE · Part D claims (CY24) · First FDA approval:
Brand-only (no generics) 1 plans require PA
Low NADAC$0.026
Avg plan cost$0.640
Part D spend 25× spread, current vs floor
Class share
0%
of class CY24 spend
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04
Escitalopram
Brand: Lexapro · Part D claims (CY24) · First FDA approval:
14 generic mfrs 9 plans require PA
Low NADAC$0.041
Avg plan cost$0.882
Part D spend 22× spread, current vs floor
Class share
0%
of class CY24 spend
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