Voclosporin vs Cyclosporine Ophthalmic Solution — Cost, Coverage & Plan Comparison

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Up to 4 drugsCross-class or same-class

Start with the molecules your plan spends the most on. Most useful comparisons live within the same therapeutic class — switching across classes requires deeper clinical review.

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Federal data onlyNo PBM pricing assumed

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11 dimensions

Calcineurin Inhibitor Immunosuppressant

Voclosporin

Brand: LUPKYNIS

First FDA approval: 2021-01-22

Calcineurin Inhibitor Immunosuppressant

Cyclosporine Ophthalmic Solution

Brand: VEVYE

First FDA approval: 2023-12-01

Lowest NADACAcquisition cost floor across all NDCs

—Per unit

$368.54Per unit

Average NADACAcross all dosage forms and strengths

—

$368.54Up to $368.54

Generic manufacturersActive ANDA holders — FDA Orange Book

00 total ANDAs filed

Annualized Part D spendCY2024 — CMS Part D Spending Dashboard

$41.3MFull year

—Full year

Part D claims (CY24)Total fills, all strengths

3K647 beneficiaries

—— beneficiaries

Avg cost per claimCalculated: total spend ÷ total claims

$12,609Per claim, all NDCs

—Per claim, all NDCs

Part D plans surveyed2026 plan year — CMS Formulary file

329Across CMS plan year

Prior-authorization frictionPlan-NDC pairs requiring PA

22Minimal friction

0Zero PA friction

Step therapy appliedPlan-NDC pairs requiring step therapy

0None

FDA shortage statusLive cross-reference vs FDA Drug Shortage Database

NoneClear

Generic availableFDA Orange Book

NoBrand-only