A BuiltForAI Property
Live data · NADAC + Part D CY24 · reviewed daily

Alprazolam (Xanax)

Alprazolam treats anxiety, seizures, and insomnia by enhancing GABA activity in the brain.

First FDA approval1981-10-16
Generic availableYes · 9 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one

$128.6M in CY2024 Part D spend17.4M claims · 4.1M beneficiaries · 329 plans surveyed

Lowest NADAC
$0.023/unit
20 NDCs benchmarked, lowest of all strengths.
Average NADAC
$0.023
Across all dosage forms in distribution.
Highest NADAC
$0.024
Range is tight.
Plans with PA
99 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema11 entries indexed · 4 visible
What is Alprazolam used for?

Alprazolam treats anxiety, seizures, and insomnia by enhancing GABA activity in the brain.

Is there a generic for Alprazolam?

Yes. 41 ANDAs filed at FDA, 9 generic manufacturers currently shipping.

How much does my plan pay for Alprazolam?

Across 329 Part D plans, Alprazolam averages $0.023/unit (NADAC). Lowest available: $0.023/unit. Highest in distribution: $0.024/unit.

Is Alprazolam on the FDA shortage list?

No. Alprazolam is not currently on the FDA Drug Shortage Database.

7 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Benzodiazepine6 alternatives in D1
01
Clonazepam
Brand: Klonopin
$0.021Lowest NADAC
11Generic mfrs
$113.3MCY24 Part D spend
Compare →
02
Lorazepam
Brand: Ativan
$0.034Lowest NADAC
15Generic mfrs
$123.2MCY24 Part D spend
Compare →
03
Diazepam
Brand: Valium
$0.021Lowest NADAC
16Generic mfrs
$75.9MCY24 Part D spend
Compare →
04
Temazepam
Brand: RESTORIL
$0.079Lowest NADAC
7Generic mfrs
$41.1MCY24 Part D spend
Compare →
05
Clobazam
Brand: Onfi
$0.155Lowest NADAC
14Generic mfrs
$82.4MCY24 Part D spend
Compare →
06
Chlordiazepoxide
Benzodiazepine
$0.142Lowest NADAC
3Generic mfrs
$1.5MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (10 approvals on file) · NADAC unit costs: CMS NADAC weekly file (20 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard (CY2024) · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.