Class summary at a glance.

Every drug in the Benzodiazepine class tracked across NADAC, Part D Formulary, Part D Spending, FDA Orange Book, and shortage data. Ranked below by CY24 Part D spend. Click any molecule for the full drug profile.

Molecules in class: 22tracked in Part D
CY24 Part D spend: $638.0Mcombined across class
Total Rx claims: 51.3M12.4M unique beneficiaries
Generic mfrs (active): 94across all molecules

Every drug in this class, ranked by Part D spend.

CY2024 dataCMS Part D Spending Dashboard

Alprazolam

Brand: Xanax · 17.4M Part D claims (CY24) · 4.1M beneficiaries · First FDA approval: 1981-10-16

9 generic mfrs 99 plans require PA

Low NADAC$0.023

→

Avg plan cost$1.55

Part D spend $128.6M 68× spread, current vs floor

Class share

20%

of class CY24 spend

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Lorazepam

Brand: Ativan · 12.1M Part D claims (CY24) · 3.3M beneficiaries · First FDA approval: 1980-07-25

15 generic mfrs 328 plans require PA Active FDA shortage

Low NADAC$0.034

→

Avg plan cost$1.12

Part D spend $123.2M 33× spread, current vs floor

Class share

19%

of class CY24 spend

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Clonazepam

Brand: Klonopin · 13.2M Part D claims (CY24) · 2.4M beneficiaries · First FDA approval: 1975-06-02

11 generic mfrs 56 plans require PA Active FDA shortage

Low NADAC$0.021

→

Avg plan cost$0.298

Part D spend $113.3M 14× spread, current vs floor

Class share

18%

of class CY24 spend

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Clobazam

Brand: Onfi · 285K Part D claims (CY24) · 44K beneficiaries · First FDA approval: 2012-12-14

14 generic mfrs 1396 plans require PA

Low NADAC$0.155

→

Avg plan cost$7.17

Part D spend $82.4M 46× spread, current vs floor

Class share

13%

of class CY24 spend

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Diazepam

Brand: Valium · 4.5M Part D claims (CY24) · 1.6M beneficiaries · First FDA approval: 1963-11-15

16 generic mfrs 965 plans require PA

Low NADAC$0.021

→

Avg plan cost$89.64

Part D spend $75.9M 4246× spread, current vs floor

Class share

12%

of class CY24 spend

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Midazolam

Brand: MIDAZOLAM · 100K Part D claims (CY24) · 65K beneficiaries · First FDA approval: 2000-06-20

9 generic mfrs 89 plans require PA Active FDA shortage

Low NADAC$0.240

→

Avg plan cost$22.28

Part D spend $58.3M 93× spread, current vs floor

Class share

of class CY24 spend

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Temazepam

Brand: RESTORIL · 3.3M Part D claims (CY24) · 664K beneficiaries · First FDA approval: 1981-02-27

7 generic mfrs 279 plans require PA

Low NADAC$0.079

→

Avg plan cost$0.415

Part D spend $41.1M 5× spread, current vs floor

Class share

of class CY24 spend

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Estazolam

95K Part D claims (CY24) · 19K beneficiaries · First FDA approval: 1997-10-01

3 generic mfrs 8 plans require PA

Low NADAC$0.668

→

Avg plan cost$0.753

Part D spend $5.7M 1× spread, current vs floor

Class share

of class CY24 spend

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Triazolam

Brand: Halcion · 155K Part D claims (CY24) · 78K beneficiaries · First FDA approval: 1982-11-15

2 generic mfrs 14 plans require PA Discontinued

Low NADAC$0.321

→

Avg plan cost$0.346

Part D spend $5.3M 1× spread, current vs floor

Class share

of class CY24 spend

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Oxazepam

47K Part D claims (CY24) · 10K beneficiaries · First FDA approval: 2007-01-02

4 generic mfrs 69 plans require PA

Low NADAC$0.789

→

Avg plan cost$1.01

Part D spend $2.7M 1× spread, current vs floor

Class share

of class CY24 spend

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Chlordiazepoxide

145K Part D claims (CY24) · 44K beneficiaries · First FDA approval: 1976-06-15

3 generic mfrs 30 plans require PA

Low NADAC$0.142

→

Avg plan cost$0.164

Part D spend $1.5M 1× spread, current vs floor

Class share

of class CY24 spend

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Alprazolam C-Iv

— Part D claims (CY24) · First FDA approval: 2023-03-14

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

of class CY24 spend

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Alprazolam Odt C-Iv

— Part D claims (CY24) · First FDA approval: 2025-08-22

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

of class CY24 spend

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Chlordiazepoxide and Amitriptyline

— Part D claims (CY24) · First FDA approval: 1986-12-10

1 generic mfrs 14 plans require PA

Low NADAC$1.20

→

Avg plan cost$1.39

Part D spend — 1× spread, current vs floor

Class share

of class CY24 spend

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Chlordiazepoxide and Clidinium

Brand: Librax · — Part D claims (CY24) · First FDA approval: 1966-09-01

Brand-only (no generics)

Low NADAC$0.240

→

Avg plan cost$0.240

Part D spend — 1× spread, current vs floor

Class share

of class CY24 spend

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Diazepam Intensol

— Part D claims (CY24) · First FDA approval: 1987-04-03

Brand-only (no generics) 157 plans require PA

Low NADAC$0.995

→

Avg plan cost$0.995

Part D spend — 1× spread, current vs floor

Class share

of class CY24 spend

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Diazepam Oral

Brand: Diazepam · — Part D claims (CY24) · First FDA approval: 2016-06-24

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

of class CY24 spend

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Diazepam Oral Solution (Concentrate)

Brand: Diazepam · — Part D claims (CY24) · First FDA approval: 2014-04-14

Brand-only (no generics)

Low NADAC$0.995

→

Avg plan cost$0.995

Part D spend — 1× spread, current vs floor

Class share

of class CY24 spend

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Midazolam In

— Part D claims (CY24) · First FDA approval: 2025-10-15

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

of class CY24 spend

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Midazolam Injection,

— Part D claims (CY24) · First FDA approval: 2022-08-08

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

of class CY24 spend

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Quazepam

— Part D claims (CY24) · First FDA approval: 2018-03-20

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

of class CY24 spend

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Temazepam Civ

Brand: Temazepam · — Part D claims (CY24) · First FDA approval: 1990-09-30

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

of class CY24 spend

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Class summary at a glance.

Every drug in this class, ranked by Part D spend.

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