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Chlordiazepoxide and Amitriptyline

Chlordiazepoxide and Amitriptyline treats anxiety, seizures, and insomnia by enhancing GABA activity in the brain.

First FDA approval1986-12-10
Generic availableYes · 1 mfrs
Shortage statusNone
340B exposureunknown
Last updated
NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annual (CY24)Orange Book: weeklyShortages: daily
At a glance · the numbers a plan sponsor wants on screen one
Lowest NADAC
$1.20/unit
4 NDCs benchmarked, lowest of all strengths.
Average NADAC
$1.39
Across all dosage forms in distribution.
Highest NADAC
$1.58
Range is tight.
Plans with PA
14 / 329
Limited PA friction.

Questions a plan sponsor actually asks.

FAQPage schema8 entries indexed · 4 visible
What is Chlordiazepoxide and Amitriptyline used for?

Chlordiazepoxide and Amitriptyline treats anxiety, seizures, and insomnia by enhancing GABA activity in the brain.

Is there a generic for Chlordiazepoxide and Amitriptyline?

Yes. 2 ANDAs filed at FDA, 1 generic manufacturers currently shipping.

How much does my plan pay for Chlordiazepoxide and Amitriptyline?

Across 329 Part D plans, Chlordiazepoxide and Amitriptyline averages $1.39/unit (NADAC). Lowest available: $1.20/unit. Highest in distribution: $1.58/unit.

Is Chlordiazepoxide and Amitriptyline on the FDA shortage list?

No. Chlordiazepoxide and Amitriptyline is not currently on the FDA Drug Shortage Database.

4 additional drug-specific questions are indexed in the page's FAQPage schema for search engines and LLM crawlers, beyond what renders visually above. View page source for the complete JSON-LD.

Same class. Different math.

Benzodiazepine6 alternatives in D1
01
Alprazolam
Brand: Xanax
$0.023Lowest NADAC
9Generic mfrs
$128.6MCY24 Part D spend
Compare →
02
Clonazepam
Brand: Klonopin
$0.021Lowest NADAC
11Generic mfrs
$113.3MCY24 Part D spend
Compare →
03
Lorazepam
Brand: Ativan
$0.034Lowest NADAC
15Generic mfrs
$123.2MCY24 Part D spend
Compare →
04
Diazepam
Brand: Valium
$0.021Lowest NADAC
16Generic mfrs
$75.9MCY24 Part D spend
Compare →
05
Temazepam
Brand: RESTORIL
$0.079Lowest NADAC
7Generic mfrs
$41.1MCY24 Part D spend
Compare →
06
Clobazam
Brand: Onfi
$0.155Lowest NADAC
14Generic mfrs
$82.4MCY24 Part D spend
Compare →

Sources · every number above traces back.

Last refresh30 May 2026

Drug identity, dosage forms, brand names: openFDA NDC Directory · First approval, ANDA history: FDA Orange Book (2 approvals on file) · NADAC unit costs: CMS NADAC weekly file (4 NDCs benchmarked) · Formulary tier and PA placement: CMS Part D Formulary file (329 plans) · Annualized spend, claims, beneficiaries: CMS Part D Spending Dashboard · Shortage status: FDA Drug Shortage Database · 340B exposure: HRSA OPAIS. Methodology and reproducibility notes on /methodology.