Drug class profile · refreshed daily from federal data

Corticosteroid

68 molecules in this class, $1.26B combined CY2024 Part D spend across 62.1M claims. Class-level guide below for benefits decision-makers: where the money lives, where the savings live.

Last updated 15 Jul 2026

NADAC: weekly (every Wed)Part D Formulary: quarterlyPart D Spend: annualOrange Book: weeklyShortages: daily

Class summary at a glance.

Every drug in the Corticosteroid class tracked across NADAC, Part D Formulary, Part D Spending, FDA Orange Book, and shortage data. Ranked below by CY24 Part D spend. Click any molecule for the full drug profile.

Molecules in class: 68tracked in Part D
CY24 Part D spend: $1.26Bcombined across class
Total Rx claims: 62.1M37.0M unique beneficiaries
Generic mfrs (active): 249across all molecules

Every drug in this class, ranked by Part D spend.

CY2024 dataCMS Part D Spending Dashboard

01

Budesonide

Brand: Eohilia · 972K Part D claims (CY24) · 358K beneficiaries · First FDA approval: 2000-09-08

15 generic mfrs 1181 plans require PA

Low NADAC$0.513

→

Avg plan cost$11.97

Part D spend $299.4M 23× spread, current vs floor

Class share

24%

of class CY24 spend

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02

Prednisolone

Brand: PRED FORTE · 5.9M Part D claims (CY24) · 3.5M beneficiaries · First FDA approval: 1972-12-01

16 generic mfrs 6 plans require PA

Low NADAC$0.576

→

Avg plan cost$8.83

Part D spend $240.2M 15× spread, current vs floor

Class share

19%

of class CY24 spend

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03

Prednisone

24.2M Part D claims (CY24) · 12.7M beneficiaries · First FDA approval: 1972-04-21

13 generic mfrs 1052 plans require PA

Low NADAC$0.037

→

Avg plan cost$0.114

Part D spend $118.1M 3× spread, current vs floor

Class share

9%

of class CY24 spend

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04

Triamcinolone Acetonide

Brand: KENALOG-10 · 10.1M Part D claims (CY24) · 6.3M beneficiaries · First FDA approval: 1978-02-14

27 generic mfrs 0 plans require PA Active FDA shortage

Low NADAC$0.025

→

Avg plan cost$1.81

Part D spend $105.6M 74× spread, current vs floor

Class share

8%

of class CY24 spend

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05

Hydrocortisone

Brand: ANUCORT-HC · 4.5M Part D claims (CY24) · 2.5M beneficiaries · First FDA approval: 1952-12-15

24 generic mfrs 0 plans require PA

Low NADAC$0.064

→

Avg plan cost$0.862

Part D spend $93.8M 13× spread, current vs floor

Class share

7%

of class CY24 spend

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06

Mometasone Furoate

1.6M Part D claims (CY24) · 885K beneficiaries · First FDA approval: 2024-03-18

10 generic mfrs

Low NADAC$1.60

→

Avg plan cost$1.60

Part D spend $78.9M 1× spread, current vs floor

Class share

6%

of class CY24 spend

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07

Methylprednisolone

Brand: DEPO-MEDROL · 9.0M Part D claims (CY24) · 7.1M beneficiaries · First FDA approval: 1957-10-24

16 generic mfrs 552 plans require PA Active FDA shortage

Low NADAC$0.112

→

Avg plan cost$3.84

Part D spend $64.4M 34× spread, current vs floor

Class share

5%

of class CY24 spend

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08

Fluorometholone

Brand: FML · 646K Part D claims (CY24) · 351K beneficiaries · First FDA approval: 1972-02-01

2 generic mfrs 0 plans require PA

Low NADAC$12.58

→

Avg plan cost$21.37

Part D spend $51.2M 2× spread, current vs floor

Class share

4%

of class CY24 spend

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09

Betamethasone Dipropionate

Brand: DIPROLENE · 1.2M Part D claims (CY24) · 683K beneficiaries · First FDA approval: 1984-06-26

12 generic mfrs 0 plans require PA

Low NADAC$0.118

→

Avg plan cost$0.550

Part D spend $48.9M 5× spread, current vs floor

Class share

4%

of class CY24 spend

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10

Fluocinonide

Brand: Fluocinol Pak · 1.1M Part D claims (CY24) · 642K beneficiaries · First FDA approval: 1984-06-26

16 generic mfrs 0 plans require PA

Low NADAC$0.152

→

Avg plan cost$0.439

Part D spend $46.3M 3× spread, current vs floor

Class share

4%

of class CY24 spend

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11

Dexamethasone

Brand: DEXTENZA · 2.4M Part D claims (CY24) · 1.5M beneficiaries · First FDA approval: 1975-05-19

20 generic mfrs 5 plans require PA Active FDA shortage

Low NADAC$0.029

→

Avg plan cost$0.383

Part D spend $35.4M 13× spread, current vs floor

Class share

3%

of class CY24 spend

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12

Deflazacort

Brand: EMFLAZA · 2K Part D claims (CY24) · 263 beneficiaries · First FDA approval: 2018-09-10

8 generic mfrs 208 plans require PA

Low NADAC—

→

Avg plan cost—

Part D spend $25.2M

Class share

2%

of class CY24 spend

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13

Desonide

Brand: Tridesilon Cream · 279K Part D claims (CY24) · 200K beneficiaries · First FDA approval: 1992-06-30

8 generic mfrs 0 plans require PA Discontinued

Low NADAC$0.189

→

Avg plan cost$0.323

Part D spend $14.5M 2× spread, current vs floor

Class share

1%

of class CY24 spend

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14

Fluocinolone Acetonide

Brand: DERMA-SMOOTHE/FS · 214K Part D claims (CY24) · 138K beneficiaries · First FDA approval: 1982-12-16

12 generic mfrs 0 plans require PA

Low NADAC$0.171

→

Avg plan cost$0.724

Part D spend $10.7M 4× spread, current vs floor

Class share

1%

of class CY24 spend

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15

Amcinonide

5K Part D claims (CY24) · 2K beneficiaries · First FDA approval: 2003-03-19

4 generic mfrs 0 plans require PA

Low NADAC$4.90

→

Avg plan cost$4.90

Part D spend $8.9M 1× spread, current vs floor

Class share

1%

of class CY24 spend

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16

Desoximetasone

Brand: Topicort · 67K Part D claims (CY24) · 41K beneficiaries · First FDA approval: 1985-01-17

11 generic mfrs 0 plans require PA

Low NADAC$0.273

→

Avg plan cost$0.586

Part D spend $4.9M 2× spread, current vs floor

Class share

0%

of class CY24 spend

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17

Flurandrenolide

Brand: CORDRAN · 5K Part D claims (CY24) · 3K beneficiaries · First FDA approval: 2016-10-06

2 generic mfrs 0 plans require PA

Low NADAC$1.16

→

Avg plan cost$1.16

Part D spend $4.4M 1× spread, current vs floor

Class share

0%

of class CY24 spend

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18

Halcinonide

Brand: HALOG · 2K Part D claims (CY24) · 1K beneficiaries · First FDA approval: 2009-01-01

3 generic mfrs 0 plans require PA

Low NADAC$6.08

→

Avg plan cost$6.08

Part D spend $2.5M 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

19

Alclometasone Dipropionate

51K Part D claims (CY24) · 36K beneficiaries · First FDA approval: 2004-07-29

2 generic mfrs 0 plans require PA

Low NADAC$0.493

→

Avg plan cost$1.27

Part D spend $2.2M 3× spread, current vs floor

Class share

0%

of class CY24 spend

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20

Albuterol and Budesonide

Brand: AIRSUPRA · — Part D claims (CY24) · First FDA approval: 2023-10-02

Brand-only (no generics) 2 plans require PA

Low NADAC$45.06

→

Avg plan cost$45.06

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

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21

Budesonide Inhalation

— Part D claims (CY24) · First FDA approval: 2019-05-21

Brand-only (no generics)

Low NADAC$0.693

→

Avg plan cost$0.693

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

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22

Budesonide and Formoterol

Brand: BREYNA · — Part D claims (CY24) · First FDA approval: 2023-07-31

1 generic mfrs 0 plans require PA

Low NADAC$20.48

→

Avg plan cost$21.70

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

23

Budesonide and Formoterol Fumarate

Brand: SYMBICORT · — Part D claims (CY24) · First FDA approval: 2007-05-29

Brand-only (no generics) 0 plans require PA

Low NADAC$16.80

→

Avg plan cost$20.15

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

24

Budesonide, Glycopyrrolate, and Formoterol

Brand: BREZTRI · — Part D claims (CY24) · First FDA approval: 2020-07-23

Brand-only (no generics) 0 plans require PA

Low NADAC$61.31

→

Avg plan cost$61.38

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

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25

Ciprofloxacin and Dexamethasone

Brand: Ciprofloxacin and Dexamethasone · — Part D claims (CY24) · First FDA approval: 2020-08-10

5 generic mfrs 0 plans require PA

Low NADAC$7.34

→

Avg plan cost$7.34

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

26

Ciprofloxacin and Hydrocortisone

Brand: CIPRO · — Part D claims (CY24) · First FDA approval: 1999-03-15

1 generic mfrs 0 plans require PA

Low NADAC$34.87

→

Avg plan cost$34.87

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

27

Deflazacort Oral

— Part D claims (CY24) · First FDA approval: 2024-05-01

Brand-only (no generics) 23 plans require PA

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

0%

of class CY24 spend

View profile →

28

Desonide Ointment,

— Part D claims (CY24) · First FDA approval: 2019-03-20

Brand-only (no generics)

Low NADAC$0.263

→

Avg plan cost$0.323

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

29

Dexamethasone Intensol

— Part D claims (CY24) · First FDA approval: 1983-09-01

Brand-only (no generics)

Low NADAC$0.743

→

Avg plan cost$0.743

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

30

Dexamethasone Sodium

Brand: DMT SUIK · — Part D claims (CY24) · First FDA approval: 1975-07-15

Brand-only (no generics) 0 plans require PA

Low NADAC$0.203

→

Avg plan cost$1.08

Part D spend — 5× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

31

Dr Adam Au

— Part D claims (CY24) · First FDA approval: 2002-07-12

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

0%

of class CY24 spend

View profile →

32

Fluocinolone Acetonide Topical

— Part D claims (CY24) · First FDA approval: 2016-12-07

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

0%

of class CY24 spend

View profile →

33

Fluocinolone Acetonide Topical Solution Usp,

— Part D claims (CY24) · First FDA approval: 2019-03-20

Brand-only (no generics)

Low NADAC$0.197

→

Avg plan cost$0.197

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

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34

Fluocinolone Acetonide, Hydroquinone, and Tretinoin

Brand: TRI-LUMA · — Part D claims (CY24) · First FDA approval: 2002-01-18

Brand-only (no generics)

Low NADAC$7.82

→

Avg plan cost$7.82

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

35

Fluocinonide Topical Solution Usp,

Brand: Fluocinonide · — Part D claims (CY24) · First FDA approval: 2019-04-19

Brand-only (no generics) 0 plans require PA

Low NADAC$0.214

→

Avg plan cost$0.214

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

36

Fluticasone and Salmeterol

Brand: ADVAIR · — Part D claims (CY24) · First FDA approval: 2001-02-05

Brand-only (no generics) 0 plans require PA Discontinued

Low NADAC$1.14

→

Avg plan cost$46.23

Part D spend — 41× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

37

Halcinonide Cream

Brand: Halog · — Part D claims (CY24) · First FDA approval: 2009-02-10

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

0%

of class CY24 spend

View profile →

38

Halcinonide Topical

Brand: HALOG · — Part D claims (CY24) · First FDA approval: 2025-01-29

Brand-only (no generics)

Low NADAC$6.08

→

Avg plan cost$6.08

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

39

Halobetasol

Brand: Bryhali · — Part D claims (CY24) · First FDA approval: 2004-12-16

4 generic mfrs 0 plans require PA

Low NADAC$0.433

→

Avg plan cost$0.577

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

40

Hydrocortisone Cream

— Part D claims (CY24) · First FDA approval: 2024-05-30

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

0%

of class CY24 spend

View profile →

41

Hydrocortisone Lotion

Brand: Hydrocortisone · — Part D claims (CY24) · First FDA approval: 2024-06-10

Brand-only (no generics) 0 plans require PA

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

0%

of class CY24 spend

View profile →

42

Hydrocortisone and Acetic Acid

— Part D claims (CY24) · First FDA approval: 2005-04-28

Brand-only (no generics) 0 plans require PA

Low NADAC$5.95

→

Avg plan cost$5.95

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

43

Hydrocortisone and Acetic Acid Otic

Brand: hydrocortisone and acetic acid · — Part D claims (CY24) · First FDA approval: 2024-02-23

Brand-only (no generics)

Low NADAC$5.95

→

Avg plan cost$5.95

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

44

Hydrocortisone and Iodoquinol

Brand: Hydrocortisone Iodoquinol · — Part D claims (CY24) · First FDA approval: 2020-09-17

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

0%

of class CY24 spend

View profile →

45

Hydrocortisone, Iodoquinol

— Part D claims (CY24) · First FDA approval: 2018-10-16

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

0%

of class CY24 spend

View profile →

46

Loteprednol

Brand: Alrex · — Part D claims (CY24) · First FDA approval: 1998-03-09

5 generic mfrs 24 plans require PA

Low NADAC$10.37

→

Avg plan cost$29.75

Part D spend — 3× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

47

Methylprednisolone Sodium

Brand: SOLU-MEDROL · — Part D claims (CY24) · First FDA approval: 1959-04-02

Brand-only (no generics)

Low NADAC$4.04

→

Avg plan cost$5.84

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

48

Mometasone

Brand: ASMANEX · — Part D claims (CY24) · First FDA approval: 2004-12-03

Brand-only (no generics) 1 plans require PA

Low NADAC$0.217

→

Avg plan cost$21.96

Part D spend — 101× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

49

Neo/Poly-B/Dex Ophth Oint

— Part D claims (CY24) · First FDA approval: 2024-01-12

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

0%

of class CY24 spend

View profile →

50

Neomycin Sulfate, Polymyxin B Sulfate, Hydrocortisone

Brand: NEOMYCIN AND POLYMYXIN B SULFATES AND HYDROCORTISONE · — Part D claims (CY24) · First FDA approval: 1995-12-29

4 generic mfrs 0 plans require PA

Low NADAC$5.27

→

Avg plan cost$5.27

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

51

Neomycin Sulfate, Polymyxin B Sulfate, and Dexamethasone

Brand: Neomycin and Polymyxin B Sulfates and Dexamethasone · — Part D claims (CY24) · First FDA approval: 1994-07-25

Brand-only (no generics) 0 plans require PA

Low NADAC$2.75

→

Avg plan cost$2.75

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

52

Neomycin Sulfate, Polymyxin B and Dexamethasone

Brand: MAXITROL · — Part D claims (CY24) · First FDA approval: 1964-11-15

3 generic mfrs 0 plans require PA

Low NADAC$1.63

→

Avg plan cost$1.63

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

53

Neomycin Sulfate, Polymyxin B and Dexamethasone Suspension/ Drops

Brand: NEOMYCIN POLYMYXIN B SULFATES AND DEXAMETHASONE · — Part D claims (CY24) · First FDA approval: 2022-01-18

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

0%

of class CY24 spend

View profile →

54

Neomycin Sulfate, Polymyxin B and Hydrocortisone

Brand: NEOMYCIN AND POLYMYXIN B SULFATES AND HYDROCORTISONE · — Part D claims (CY24) · First FDA approval: 1996-08-28

Brand-only (no generics) 0 plans require PA

Low NADAC$3.83

→

Avg plan cost$8.70

Part D spend — 2× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

55

Neomycin and Fluocinolone Acetonide

Brand: Neo-Synalar · — Part D claims (CY24) · First FDA approval: 1963-06-11

1 generic mfrs 0 plans require PA

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

0%

of class CY24 spend

View profile →

56

Neomycin and Polymyxin B Sulfate, Bacitracin Zinc and Hydrocortisone

Brand: Neomycin and Polymyxin B Sulfates, Bacitracin Zinc and Hydrocortisone · — Part D claims (CY24) · First FDA approval: 1995-10-30

2 generic mfrs 0 plans require PA

Low NADAC$5.19

→

Avg plan cost$5.19

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

57

Neomycin and Polymyxin B Sulfates and Dexamethasone

— Part D claims (CY24) · First FDA approval: 1996-02-21

Brand-only (no generics)

Low NADAC$2.75

→

Avg plan cost$2.75

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

58

Neomycin and Polymyxin B Sulfates and Hydrocortisone Otic

Brand: Neomycin and Polymyxin B Sulfates and Hydrocortisone Otic Suspension · — Part D claims (CY24) · First FDA approval: 2019-03-15

Brand-only (no generics)

Low NADAC$3.83

→

Avg plan cost$3.83

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

59

Neomycin, Polymyxin B Sulfates, Dexamethasone

Brand: Neomycin and Polymyxin B Sulfates and Dexamethasone · — Part D claims (CY24) · First FDA approval: 2014-07-03

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

0%

of class CY24 spend

View profile →

60

Prednisolone Oral

Brand: Prednisolone · — Part D claims (CY24) · First FDA approval: 2022-11-20

Brand-only (no generics) 147 plans require PA

Low NADAC$0.576

→

Avg plan cost$0.590

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

61

Prednisolone Oral Solution

Brand: Prednisolone · — Part D claims (CY24) · First FDA approval: 2025-03-01

Brand-only (no generics)

Low NADAC$0.576

→

Avg plan cost$0.590

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

62

Prednisolone Sodium

Brand: Orapred · — Part D claims (CY24) · First FDA approval: 1994-07-29

Brand-only (no generics) 320 plans require PA

Low NADAC$0.106

→

Avg plan cost$1.25

Part D spend — 12× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

63

Prednisone D/P

— Part D claims (CY24) · First FDA approval: 2025-10-21

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

0%

of class CY24 spend

View profile →

64

Prednisone Intensol

— Part D claims (CY24) · First FDA approval: 1985-02-20

Brand-only (no generics) 68 plans require PA

Low NADAC$3.12

→

Avg plan cost$3.12

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

65

Tobramycin and Dexamethasone

Brand: TobraDex · — Part D claims (CY24) · First FDA approval: 1988-10-15

2 generic mfrs 0 plans require PA

Low NADAC$4.28

→

Avg plan cost$18.85

Part D spend — 4× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

66

Tolnaftate, Hydrocortisone

Brand: Mycozyl HC · — Part D claims (CY24) · First FDA approval: 2023-12-11

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

0%

of class CY24 spend

View profile →

67

Triamcinolone Acetonide Cream

Brand: TRIAMCINOLONE ACETONIDE · — Part D claims (CY24) · First FDA approval: 2022-03-01

Brand-only (no generics)

Low NADAC—

→

Avg plan cost—

Part D spend —

Class share

0%

of class CY24 spend

View profile →

68

Triamcinolone Acetonide Ointment Usp,

Brand: Triamcinolone Acetonide · — Part D claims (CY24) · First FDA approval: 2019-12-02

Brand-only (no generics)

Low NADAC$0.168

→

Avg plan cost$0.168

Part D spend — 1× spread, current vs floor

Class share

0%

of class CY24 spend

View profile →

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