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Live FDA data · refreshed daily at 06:00 UTC

89 Part D drugs are in active shortage right now.

The FDA Drug Shortage Database, cross-referenced against the 3,186-drug Part D-relevant universe and grouped by drug. Every entry links to the drug profile on RxFinder.

Last updated
Refresh cadence: daily at 06:00 UTCSource: FDA Drug Shortage DatabaseCross-referenced against 3,186-drug Part D universe

The view at a glance.

Active shortages skew toward injectables, controlled substances, and drugs with concentrated API sourcing. Several months-long shortages directly affect commercial Part D members; many require plan-side workarounds: prior-auth carveouts, alternative-product coverage, or quantity-limit suspension. Discontinued drugs are not shown here — those have stopped manufacture permanently.

Active shortages
89of 3,186 Part D drugs
Part D spend in shortage
$3.83Bcombined CY24
Top reason cited
Other53 of 89
Median shortage age
1928days since first reported

Every drug in active shortage right now.

89 drugsShowing top 50 by report date
01
Atropine Sulfate
Brand: Atropine Sulfate · Unspecified class · 9 generic mfrs · Reported: · 5263 days in active shortage
Check wholesalers for inventory Accord Healthcare Inc. · Fresenius Kabi USA
Plans affected329
·
CY24 claims327K
Part D spend $13.6M 193K beneficiaries affected
Plan action
Source check
Verify NDC availability
Drug profile →
02
Atropine Sulfate Injection
Brand: Atropine Sulfate · Unspecified class · 0 generic mfrs · Reported: · 5263 days in active shortage
Unspecified Medefil · Inc.
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
03
Fentanyl
Brand: Fentanyl system · Opioid Agonist · 5 generic mfrs · Reported: · 5263 days in active shortage
Inventory available in vial presentations. Hikma Pharmaceuticals USA · Inc.
Plans affected329
·
CY24 claims1.2M
Part D spend $139.6M 205K beneficiaries affected
Plan action
High priority
Member-impact modeling
Drug profile →
04
Lidocaine Hci and Epinephrine
alpha-Adrenergic Agonist · 3 generic mfrs · Reported: · 5211 days in active shortage
Limited Supply Available. Next Delivery and Estimated Recove Hospira · Inc.
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
05
Lidocaine Hydrochloride
Brand: AKTEN · Antiarrhythmic · 25 generic mfrs · Reported: · 5211 days in active shortage
Check wholesalers for inventory Eugia US LLC · Fresenius Kabi USA
Plans affected329
·
CY24 claims
Part D spend  
Plan action
Source check
Verify NDC availability
Drug profile →
06
Cefotaxime
Unspecified class · 0 generic mfrs · Reported: · 4120 days in active shortage
Shortage duration is unknown at this time. Hikma Pharmaceuticals USA · Inc.
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
07
Cefotaxime Injection
Brand: Cefotaxime · Unspecified class · 0 generic mfrs · Reported: · 4120 days in active shortage
Unspecified SteriMax · Inc.
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
08
Sodium Acetate
Unspecified class · 5 generic mfrs · Reported: · 3769 days in active shortage
Check wholesalers for inventory Hospira · Inc.
Plans affected329
·
CY24 claims644
Part D spend $53859 62 beneficiaries affected
Plan action
PA carveout
Verify NDC availability
Drug profile →
09
Lidocaine Hydrochloride,Epinephrine Bitartrate
Brand: Xylocaine · Unspecified class · 0 generic mfrs · Reported: · 3515 days in active shortage
Check wholesalers for inventory Fresenius Kabi USA · LLC
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
10
Sodium Bicarbonate
Unspecified class · 9 generic mfrs · Reported: · 3377 days in active shortage
Discontinuation of the manufacture of the drug Hospira · Inc.
Plans affected329
·
CY24 claims12K
Part D spend $816240 3K beneficiaries affected
Plan action
Source check
Verify NDC availability
Drug profile →
11
Sodium Bicarbonate Injection,
Brand: SODIUM BICARBONATE · Unspecified class · 0 generic mfrs · Reported: · 3377 days in active shortage
Unspecified Long Grove Pharmaceuticals LLC
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
12
Dextrose
Brand: DEXTROSE · Unspecified class · 2 generic mfrs · Reported: · 3139 days in active shortage
Estimated recovery: May 2026 Baxter Healthcare · B. Braun Medical Inc.
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
13
Hydromorphone
Brand: Dilaudid · Opioid Agonist · 8 generic mfrs · Reported: · 3133 days in active shortage
Expected recovery: TBD Fresenius Kabi USA · LLC
Plans affected329
·
CY24 claims1.2M
Part D spend $28.7M 345K beneficiaries affected
Plan action
High priority
Member-impact modeling
Drug profile →
14
Morphine
Brand: Duramorph · Opioid Agonist · 15 generic mfrs · Reported: · 3133 days in active shortage
Product temporarily on backorder. Additional lots will be a Hikma Pharmaceuticals USA · Inc.
Plans affected329
·
CY24 claims3.8M
Part D spend $108.2M 823K beneficiaries affected
Plan action
High priority
Member-impact modeling
Drug profile →
15
Dobutamine
Brand: Dobutamine Hydrochloride in Dextrose · Unspecified class · 3 generic mfrs · Reported: · 3127 days in active shortage
Distributed by Slate Run Pharmaceuticals Hospira · Inc.
Plans affected329
·
CY24 claims233
Part D spend $23938 16 beneficiaries affected
Plan action
PA carveout
Verify NDC availability
Drug profile →
16
Dobutamine In Dextrose
Unspecified class · 0 generic mfrs · Reported: · 3127 days in active shortage
Next Delivery: April 2026; Estimated Recovery: June 2026; Sh Hospira · Inc.
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
17
Dopamine
Brand: Dopamine Hydrochloride and Dextrose · Unspecified class · 1 generic mfrs · Reported: · 3127 days in active shortage
Recovery duration unknown at this time Hikma Pharmaceuticals USA · Inc.
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
18
Dopamine Hydrochloride In Dextrose
Unspecified class · 0 generic mfrs · Reported: · 3127 days in active shortage
Next Delivery and Estimated Recovery: December 2027; Shortag Hospira · Inc.
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
19
Heparin
Unfractionated Heparin · 9 generic mfrs · Reported: · 3119 days in active shortage
Product Discontinued Baxter Healthcare · Fresenius Kabi USA
Plans affected329
·
CY24 claims
Part D spend  
Plan action
Source check
Verify NDC availability
Drug profile →
20
Heparin Sodium In Sodium
Unspecified class · 0 generic mfrs · Reported: · 3119 days in active shortage
Unspecified B. Braun Medical Inc.
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
21
Bumetanide
Brand: Bumex · Loop Diuretic · 19 generic mfrs · Reported: · 3090 days in active shortage
Check wholesalers for inventory MSN Laboratories Private Limited · Fresenius Kabi USA
Plans affected329
·
CY24 claims3.7M
Part D spend $116.6M 1.0M beneficiaries affected
Plan action
High priority
Member-impact modeling
Drug profile →
22
Bupivacaine
Brand: Bupivacine HCl · Amide Local Anesthetic · 10 generic mfrs · Reported: · 3021 days in active shortage
Check wholesalers for inventory Eugia US LLC · Hospira
Plans affected329
·
CY24 claims335
Part D spend $6882 187 beneficiaries affected
Plan action
Source check
Verify NDC availability
Drug profile →
23
Bupivacaine Hci and Epinephrine
Unspecified class · 3 generic mfrs · Reported: · 3021 days in active shortage
Next Delivery and Estimated Recovery: December 2028; Shortag Hospira · Inc.
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
24
Bupivacaine Hydrochloride In Dextrose
Brand: Bupivacaine · Unspecified class · 0 generic mfrs · Reported: · 3021 days in active shortage
Next Delivery and Estimated Recovery: June 2026; Shortage pe Hospira · Inc.
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
25
Ketorolac Tromethamine
Brand: ACULAR LS · NSAID (Nonsteroidal Anti-Inflammatory Drug) · 21 generic mfrs · Reported: · 2990 days in active shortage
Athenex is not active Baxter Healthcare · Alembic Pharmaceuticals
Plans affected329
·
CY24 claims2.6M
Part D spend $54.0M 1.6M beneficiaries affected
Plan action
High priority
Member-impact modeling
Drug profile →
26
Ropivacaine
Brand: NAROPIN · Amide Local Anesthetic · 12 generic mfrs · Reported: · 2990 days in active shortage
Marketed by Sagent Pharmaceuticals InfoRLife SA · Fresenius Kabi USA
Plans affected329
·
CY24 claims
Part D spend  
Plan action
Source check
Verify NDC availability
Drug profile →
27
Lorazepam
Brand: Ativan · Benzodiazepine · 15 generic mfrs · Reported: · 2949 days in active shortage
Unavailable Hikma Pharmaceuticals USA · Inc.
Plans affected329
·
CY24 claims12.1M
Part D spend $123.2M 3.3M beneficiaries affected
Plan action
High priority
Member-impact modeling
Drug profile →
28
Dexamethasone
Brand: DEXTENZA · Corticosteroid · 20 generic mfrs · Reported: · 2668 days in active shortage
Product will be made available as it is released. Hikma Pharmaceuticals USA · Inc.
Plans affected329
·
CY24 claims2.4M
Part D spend $35.4M 1.5M beneficiaries affected
Plan action
High priority
Member-impact modeling
Drug profile →
29
Echothiophate Iodide For Ophthalmic Solution
Brand: Phospholine Iodide · Unspecified class · 0 generic mfrs · Reported: · 2440 days in active shortage
Available through limited distribution by Walgreens Specialt Fera Pharmaceuticals
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
30
Rifapentine
Brand: Priftin · Rifamycin Antimycobacterial · 0 generic mfrs · Reported: · 2257 days in active shortage
Unspecified Sanofi-Aventis U.S. LLC
Plans affected329
·
CY24 claims4K
Part D spend $818510 3K beneficiaries affected
Plan action
PA carveout
Verify NDC availability
Drug profile →
31
Midazolam
Brand: MIDAZOLAM · Benzodiazepine · 9 generic mfrs · Reported: · 2249 days in active shortage
Next Delivery: April 2026; Estimated Recovery: June 2026; Ch Hospira · Inc.
Plans affected329
·
CY24 claims100K
Part D spend $58.3M 65K beneficiaries affected
Plan action
Source check
Verify NDC availability
Drug profile →
32
Furosemide
Brand: LASIX ONYU · Loop Diuretic · 21 generic mfrs · Reported: · 2244 days in active shortage
Next Delivery and Estimated Recovery: December 2027; Shortag Hospira · Inc.
Plans affected329
·
CY24 claims35.2M
Part D spend $231.6M 10.5M beneficiaries affected
Plan action
High priority
Member-impact modeling
Drug profile →
33
Hydralazine
Brand: Hydralazine · Arteriolar Vasodilator · 17 generic mfrs · Reported: · 2244 days in active shortage
Unspecified Meitheal Pharmaceuticals · Inc.
Plans affected329
·
CY24 claims9.1M
Part D spend $119.9M 2.7M beneficiaries affected
Plan action
High priority
Member-impact modeling
Drug profile →
34
Dexmedetomidine
Brand: Dexmedetomidine Hydrochloride in Sodium Chloride · Central alpha-2 Adrenergic Agonist · 24 generic mfrs · Reported: · 2241 days in active shortage
Expected recovery: TBD Fresenius Kabi USA · LLC
Plans affected329
·
CY24 claims97
Part D spend $308999 42 beneficiaries affected
Plan action
Source check
Verify NDC availability
Drug profile →
35
Isoleucine, Leucine, Lysine Acetate, Methionine, Phenylalanine, Threonine, Tryptophan, Valine, Alanine, Arginine, Aspartic Acid, Glutamic Acid, Glycine, Histidine, Proline, Serine, Taurine, and Tyrosine
Brand: Aminosyn-PF · Amino Acid · 0 generic mfrs · Reported: · 1999 days in active shortage
Estimated recovery: TBD. This product is distributed by ICU Otsuka ICU Medical LLC
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
36
Isoleucine, Leucine, Lysine Acetate, Methionine, Phenylalanine, Threonine, Tryptophan, Valine, Alanine, Arginine, Aspartic Acid, Glutamic Acid, Histidine, Proline, Serine, N-Acetyltyrosine, and Glycine
Brand: Aminosyn II · Amino Acid · 0 generic mfrs · Reported: · 1999 days in active shortage
This product is distributed by ICU Medical. For questions re Otsuka ICU Medical LLC
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
37
Isoleucine, Leucine, Lysine Acetate, Methionine, Phenylalanine, Threonine, Tryptophan, Valine, Cysteine Hydrochloride, Histidine, Tyrosine, N-Acetyl-Tyrosine, Alanine, Arginine, Proline, Serine, Glycine, Aspartic Acid, Glutamic Acid, and Taurine
Brand: TrophAmine · Amino Acid · 0 generic mfrs · Reported: · 1999 days in active shortage
On allocation B. Braun Medical Inc.
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
38
Leucine, Lysine, Isoleucine, Valine, Histidine, Phenylalanine, Threonine, Methionine, Tryptophan, Tyrosine, N-Acetyl-Tyrosine, Arginine, Proline, Alanine, Glutamic Acide, Serine, Glycine, Aspartic Acid, Taurine, Cysteine
Brand: Premasol - sulfite-free (Amino Acid) · Amino Acid · 0 generic mfrs · Reported: · 1999 days in active shortage
Unspecified Baxter Healthcare
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
43
Azacitidine
Brand: ONUREG · Nucleoside Metabolic Inhibitor · 13 generic mfrs · Reported: · 1989 days in active shortage
Additional lots are scheduled for manufacturing to meet dema Meitheal Pharmaceuticals · Inc.
Plans affected329
·
CY24 claims8K
Part D spend $138.5M 2K beneficiaries affected
Plan action
Source check
Verify NDC availability
Drug profile →
44
Valproate
Unspecified class · 3 generic mfrs · Reported: · 1977 days in active shortage
Additional lots will be available. Product will be made ava Hikma Pharmaceuticals USA · Inc.
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
45
Rifampin
Brand: Rifadin IV · Rifamycin Antibacterial · 7 generic mfrs · Reported: · 1928 days in active shortage
On allocation Lupin Pharmaceuticals · Inc.
Plans affected329
·
CY24 claims167K
Part D spend $10.7M 64K beneficiaries affected
Plan action
Source check
Verify NDC availability
Drug profile →
46
Desmopressin
Brand: DDAVP · Vasopressin Analog · 13 generic mfrs · Reported: · 1905 days in active shortage
Next replenishment expected late March 2026 Ferring · Apotex Corp.
Plans affected329
·
CY24 claims294K
Part D spend $24.1M 69K beneficiaries affected
Plan action
Source check
Verify NDC availability
Drug profile →
47
Triamcinolone Hexacetonide
Brand: Hexatrione · Unspecified class · 0 generic mfrs · Reported: · 1852 days in active shortage
Unspecified Medexus
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
48
Triamcinolone Acetonide
Brand: KENALOG-10 · Corticosteroid · 27 generic mfrs · Reported: · 1706 days in active shortage
Estimated duration: 12 months Harrow Eye · LLC
Plans affected329
·
CY24 claims10.1M
Part D spend $105.6M 6.3M beneficiaries affected
Plan action
High priority
Member-impact modeling
Drug profile →
49
Sterile Water
Unspecified class · 0 generic mfrs · Reported: · 1649 days in active shortage
Two lots available for commercial use. Expiration date 12/31 Nephron Pharmaceuticals Corporation
Plans affected329
·
CY24 claims
Part D spend  
Plan action
PA carveout
Verify NDC availability
Drug profile →
50
Sterile Water For Injection
Brand: Sterile Water · Unspecified class · 7 generic mfrs · Reported: · 1649 days in active shortage
Unspecified Medefil · Inc.
Plans affected329
·
CY24 claims
Part D spend  
Plan action
Source check
Verify NDC availability
Drug profile →