FDA Drug Shortage Database

Drug Shortages Monitor

Real-time tracking of 120 drugs currently in shortage or discontinued. Data updated daily from FDA, with manufacturer-level detail and impact analysis.

89Active Shortages

158Discontinued

120Total Drugs Affected

Most Affected Drug Classes

Amino Acid

8

Opioid Agonist

8

Corticosteroid

5

Insulin Analog

5

Benzodiazepine

4

Central Nervous System Stimulant

4

Amide Local Anesthetic

3

Azole Antifungal

3

Recently Reported

Latest shortage and discontinuation reports from FDA.

2026-03-27

Tazemetostat discontinued Discontinuation of the manufacture of the drug product Epizyme, Inc. (An Ipsen Company)

2026-03-26

Clindamycin Palmitate discontinued Discontinuation of the manufacture of the drug Amneal Pharmaceuticals

2026-03-26

Lincomycin discontinued A business decision was made to discontinue manufacture of the drug. XGen Pharmaceuticals DJB, Inc.

2026-03-26

Lincomycin discontinued A business decision was made to discontinue manufacture of the drug. XGen Pharmaceuticals DJB, Inc.

2026-03-25

Nebivolol discontinued Discontinuation of the manufacture of the drug Torrent Pharmaceuticals Limited

2026-03-25

Nebivolol discontinued Discontinuation of the manufacture of the drug Torrent Pharmaceuticals Limited

2026-03-25

Nebivolol discontinued Discontinuation of the manufacture of the drug Torrent Pharmaceuticals Limited

2026-03-25

Nebivolol discontinued Discontinuation of the manufacture of the drug Torrent Pharmaceuticals Limited

2026-03-25

Nebivolol discontinued Discontinuation of the manufacture of the drug Torrent Pharmaceuticals Limited

2026-03-25

Nebivolol discontinued Discontinuation of the manufacture of the drug Torrent Pharmaceuticals Limited

All Drugs in Shortage

Grouped by drug. Each entry shows all affected manufacturers and shortage reasons.

Tazemetostat TAZVERIK

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug product

Clindamycin Palmitate Cleocin Pediatric

Lincosamide Antibacterial

Discontinued Amneal Pharmaceuticals

Discontinuation of the manufacture of the drug

Lincomycin LINCOMYCIN

Discontinued 3 manufacturers affected

Discontinuation of the manufacture of the drug

Nebivolol Bystolic

beta-Adrenergic Blocker

Discontinued Torrent Pharmaceuticals Limited

Discontinuation of the manufacture of the drug

Ivabradine Corlanor

Hyperpolarization-activated Cyclic Nucleotide-gated Channel Blocker

Discontinued Amgen Inc.

Discontinuation of the manufacture of the drug product

Pilocarpine Qlosi

Cholinergic Receptor Agonist

Discontinued 3 manufacturers affected

Discontinuation of the manufacture of the drug.

Pentamidine Isethionate NebuPent

Discontinued 2 manufacturers affected

A business decision was made to discontinue manufacture of the drug.

Ramelteon Rozerem

Melatonin Receptor Agonist

Discontinued Takeda Pharmaceuticals USA Inc.

Product is expected to be available through June 2027.

Plerixafor Mozobil

Hematopoietic Stem Cell Mobilizer

Discontinued 2 manufacturers affected

A business decision was made to discontinue manufacture of the drug.

Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium DELFLEX

Discontinued Fresenius Medical Care North America

The NDC codes are being discontinued

Everolimus Afinitor

Kinase Inhibitor

Discontinued 6 manufacturers affected

Discontinuation of the manufacture of the drug

Itraconazole SPORANOX

Azole Antifungal

Discontinued Janssen Pharmaceuticals

Discontinuation of the manufacture of the drug

Clindamycin CLEOCIN PHOSPHATE

Lincosamide (Antibiotic)

Discontinued 3 manufacturers affected

Limited Supply Available. Next Delivery and Estimated Recovery: September 2026; Shortage per Manufacturer: Manufacturing Delay

Platinum-based Drug

Discontinued 4 manufacturers affected

A business decision was made to discontinue manufacture of the drug.

Arsenic Trioxide Trisenox

Discontinued Ingenus Pharmaceuticals LLC

A business decision was made to discontinue manufacture of the drug.

Frovatriptan FROVATRIPTAN

Discontinued 2 manufacturers affected

A business decision was made to discontinue manufacture of the drug.

Irinotecan Camptosar

Topoisomerase Inhibitor

Discontinued 5 manufacturers affected

Product not anticipated to be available beyond mid-late October 2025

Carboplatin KYXATA

Platinum-based Drug

Discontinued 12 manufacturers affected

Discontinuation of the manufacture of the drug

Nucleoside Metabolic Inhibitor

Discontinued Ingenus Pharmaceuticals LLC

Discontinuation of the manufacture of the drug

Docetaxel BEIZRAY

Microtubule Inhibitor

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Allopurinol Aloprim

Xanthine Oxidase Inhibitor

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Cefepime CEFEPIME HYDROCHLORIDE AND DEXTROSE

Cephalosporin Antibacterial

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug.

Chlorothiazide Chlorothiazide

Thiazide Diuretic

Discontinued 3 manufacturers affected

Gemfibrozil Lopid

Peroxisome Proliferator Receptor alpha Agonist

Discontinued Pfizer Inc.

Discontinuation of the manufacture of the drug.

beta-Adrenergic Blocker

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug; Expiry date of last distributed batch October 2026

Podofilox Condylox

Discontinued AbbVie Inc.

Discontinuation of the manufacture of the drug

Anticholinergic

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Fluvastatin Lescol

HMG-CoA Reductase Inhibitor (Statin)

Discontinued Sandoz Inc.

Discontinuation of the manufacture of the drug

Azithromycin AZASITE

Macrolide (Antibiotic)

Discontinued 4 manufacturers affected

Discontinuation of the manufacture of the drug

Maraviroc SELZENTRY

CCR5 Co-receptor Antagonist

Discontinued ViiV Healthcare Company

The anticipated date that GSK will cease distribution of the product is approximately August 1

Piperacillin and Tazobactam PIPERACILLIN AND TAZOBACTAM

Penicillin-class Antibacterial

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Riboflavin 5-Phosphate Ophthalmic EPIOXA CROSS-LINKING

Discontinued Glaukos Corporation

Discontinuing manufacture of the product as of June 2026.

Adalimumab-Adaz Adalimumab

Tumor Necrosis Factor Blocker

Discontinued Sandoz Inc.

Equivalent Sandoz format is available.

Caspofungin CANCIDAS

Echinocandin Antifungal

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Doxycycline Hyclate Acticlate

Tetracycline-class Drug

Discontinued 4 manufacturers affected

Discontinuation of the manufacture of the drug

Doxylamine and Pyridoxine BONJESTA

Discontinued 2 manufacturers affected

A business decision was made to discontinue manufacture of the drug.

Neostigmine Methylsulfate Bloxiverz

Cholinesterase Inhibitor

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Haloperidol HALOPERIDOL

Typical Antipsychotic

Discontinued 3 manufacturers affected

Discontinuation of the manufacture of the drug

Imipenem and Cilastatin Imipenem and Cilastatin

Penem Antibacterial

Discontinued Merck Sharp & Dohme Corp.

To be discontinued in approximately mid-2026.

Diltiazem CARTIA XT

Calcium Channel Blocker

Discontinued 3 manufacturers affected

Discontinuation of the manufacture of the drug

Hydroxychloroquine Plaquenil

DMARD (Antimalarial)

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Sodium Oxybate Lumryz

Discontinued Amneal Pharmaceuticals

Discontinuation of the manufacture of the drug

Mirikizumab-Mrkz Omvoh

Interleukin-23 Antagonist

Discontinued Eli Lilly and Co.

A business decision was made to discontinue. Distribution will end April 2026. The 200 mg/2 mL injection presentation (NDC 0002-1442-11) will remain.

Morphine Duramorph

Discontinued 12 manufacturers affected

Product temporarily on backorder. Additional lots will be available in the April - May 2026 timefrime

Carbamazepine Carbamazepin

Mood Stabilizer

Discontinued 3 manufacturers affected

Discontinuation of the manufacture of the drug

Doxercalciferol

Vitamin D2 Analog

Discontinued Sanofi-Aventis U.S. LLC

Discontinuation of the manufacture of the drug

Spironolactone Aldactone

Aldosterone Antagonist

Discontinued Pfizer Inc.

Discontinuation of the manufacture of the drug.

Ampicillin AMPICILLIN

Penicillin-class Antibacterial

Discontinued Sandoz Inc.

Discontinuation of private label only

Calcitriol Calcitrol

Vitamin D3 Analog

Discontinued 2 manufacturers affected

A business decision was made to discontinue manufacture of the drug

Sodium Chloride BACTERIOSTATIC SODIUM CHLORIDE

Discontinued 4 manufacturers affected

Discontinuation of the manufacture of the drug

Posaconazole NOXAFIL

Azole Antifungal

Discontinued Merck Sharp & Dohme Corp.

Discontinuation of the manufacture of the drug

Nilutamide Nilandron

Androgen Receptor Inhibitor

Discontinued Advanz Pharma (US) Corp.

Product to expire in March 2026; Discontinuation of the manufacture of the drug

Phenoxybenzamine

Discontinued Advanz Pharma (US) Corp.

Discontinuation of the manufacture of the drug

Potassium Chloride KLOR-CON

Potassium Supplement

Discontinued 4 manufacturers affected

Discontinuation of the manufacture of the drug product

Verapamil VERELAN PM

Calcium Channel Blocker

Discontinued Pfizer Inc.

Discontinuation of the manufacture of the drug

Anagrelide Agrylin

Platelet-reducing Agent

Discontinued 2 manufacturers affected

A business decision was made to discontinue manufacture of the drug.

Hydrochlorothiazide INZIRQO

Thiazide Diuretic

Discontinued 3 manufacturers affected

Discontinuation of the manufacture of the drug

Valsartan Diovan

Angiotensin 2 Receptor Blocker

Discontinued 2 manufacturers affected

A business decision was made to discontinue manufacture of the drug.

Montelukast SINGULAIR

Leukotriene Receptor Antagonist

Discontinued Organon

Discontinuation of the manufacture of the drug

Ceftazidime TAZICEF

Cephalosporin Antibacterial

Discontinued 3 manufacturers affected

Discontinuation of the manufacture of the drug

Palonosetron Palonosetron

Serotonin-3 Receptor Antagonist

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Somatropin GENOTROPIN

Recombinant Human Growth Hormone

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Vancomycin FIRVANQ

Glycopeptide Antibacterial

Discontinued 3 manufacturers affected

Discontinuation of the manufacture of the drug

Adalimumab-Ryvk Simlandi

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Cetrorelix Cetrorelix

Gonadotropin Releasing Hormone Receptor Antagonist

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Guanfacine GUANFACINE

Central alpha-2 Adrenergic Agonist

Discontinued 2 manufacturers affected

A business decision was made to discontinue manufacture of the drug.

Atropine Sulfate Atropine Sulfate

Discontinued 12 manufacturers affected

Check wholesalers for inventory

Calcium Chloride

Discontinued 3 manufacturers affected

Discontinuation of the manufacture of the drug

Deferiprone FERRIPROX

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug.

Epinephrine Adrenalin

alpha-Adrenergic Agonist

Discontinued 3 manufacturers affected

Discontinuation of the manufacture of the drug

Ketamine KETALAR

General Anesthetic

Discontinued Pfizer Inc.

Discontinuation of the manufacture of the drug

Lidocaine Hydrochloride AKTEN

Discontinued 16 manufacturers affected

Check wholesalers for inventory

Sodium Bicarbonate

Discontinued 9 manufacturers affected

Discontinuation of the manufacture of the drug

Atazanavir and Cobicistat EVOTAZ

Cytochrome P450 3A Inhibitor

Discontinued Bristol Myers Squibb Co.

The global Cease Manufacture date for EVOTAZ® currently is estimated to begin April 2026.

Lasmiditan Reyvow

Discontinued Eli Lilly and Co.

A business decision was made to discontinue manufacture of the 50 mg and 100 mg tablets. Distribution will end on May 31

Oxycodone and Acetaminophen ENDOCET

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Scopolamine Transdermal System

Anticholinergic

Discontinued Padagis US LLC

Discontinuation of the manufacture of the drug

Phenobarbital SEZABY

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Moxifloxacin Moxifloxacin

Fluoroquinolone Antibacterial

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Pramlintide SymlinPen

Discontinued AstraZeneca AB

Discontinuation of the manufacture of the drug.

Busulfan BUSULFEX

Alkylating Drug

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug.

Insulin Glargine BASAGLAR

Discontinued Eli Lilly and Co.

A business decision was made to discontinue manufacture of the drug.

Insulin Lispro ADMELOG

Discontinued Eli Lilly and Co.

A business decision was made to discontinue manufacture of the drug.

Insulin Lispro-Aabc LYUMJEV

Discontinued Eli Lilly and Co.

A business decision was made to discontinue manufacture of the drug.

Tranylcypromine PARNATE

Discontinued 2 manufacturers affected

Supply is expected to be depleted by 12/31/2025.

Elbasvir and Grazoprevir ZEPATIER

Hepatitis C Virus NS5A Inhibitor

Discontinued Merck Sharp & Dohme LLC

To be discontinued December 1

Pemetrexed Disodium Alimta

Folate Analog Metabolic Inhibitor

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Vigabatrin SABRIL

Anti-epileptic Agent

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Voriconazole VFEND

Azole Antifungal

Discontinued Pfizer Inc.

Discontinuation of the manufacture of the drug

Adalimumab-Afzb ABRILADA

Discontinued Pfizer Inc.

Discontinuation of the manufacture of the drug

Omeprazole Prilosec

Proton Pump Inhibitor

Discontinued Sandoz Inc.

Discontinuation of the manufacture of the drug

Cobicistat Tybost

Cytochrome P450 3A Inhibitor

Discontinued 2 manufacturers affected

Gilead plans to sell through the end of February 2026. Discontinuation of the manufacture of the drug due to business reasons.

Paricalcitol Zemplar

Vitamin D2 Analog

Discontinued AbbVie Inc.

Discontinuation of the manufacture of the drug

Quinapril Quinapril

Discontinued 7 manufacturers affected

Discontinuation of the manufacture of the drug

Oseltamivir Oseltamivir

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Fondaparinux Arixtra

Factor Xa Inhibitor

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug; Distributed by Sandoz Inc.

Tafamidis Meglumine Vyndaqel

Discontinued Pfizer Inc.

Discontinuation of the manufacture of the drug upon exhausted supply/stop sale in December 2025.

Triazolam Halcion

Discontinued Pfizer Inc.

Discontinuation of the manufacture of the drug.

Desonide Tridesilon Cream

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug.

Fluphenazine Fluphenazine Hydrochoride

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug.

Gemcitabine AVGEMSI

Nucleoside Metabolic Inhibitor

Discontinued 3 manufacturers affected

Discontinuation of the manufacture of the drug

Hydrocodone Bitartrate and Homatropine Methylbromide Hycodan

Discontinued 2 manufacturers affected

Oxycodone OXAYDO

Discontinued 2 manufacturers affected

Hikma has permanently discontinued (NDC 0054-0390-41) for the 15 mL bottle configuration. Hikma will continue to distribute Oxycodone Hydrochloride Oral Solution 5 mg/5 mL in the 500 mL bottle (NDC 0054-0390-63).

Sumatriptan IMITREX

Serotonin-1b and Serotonin-1d Receptor Agonist

Discontinued Prasco Laboratories

This product discontinuation is a business-related decision. The anticipated date that Prasco will cease distribution of the product is approximately February 28

Nondepolarizing Neuromuscular Blocker

Discontinued Sun Pharmaceutical Industries Limited

The 10 mg presentation remains available.

Azelastine and Fluticasone DYMISTA

Histamine-1 Receptor Antagonist

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Methotrexate JYLAMVO

Folate Analog Metabolic Inhibitor

Discontinued 12 manufacturers affected

Discontinuation of the manufacture of the drug

Dobutamine Dobutamine Hydrochloride in Dextrose

Discontinued 7 manufacturers affected

Distributed by Slate Run Pharmaceuticals

Dopamine Hydrochloride In Dextrose

Discontinued 3 manufacturers affected

Discontinuation of the manufacture of the drug

Finasteride PROPECIA

5-alpha Reductase Inhibitor

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug product

Celecoxib CELEBREX

Nonsteroidal Anti-inflammatory Drug

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Palivizumab Synagis

Respiratory Syncytial Virus Anti-F Protein Monoclonal Antibody

Discontinued Swedish Orphan Biovitrum AB

Discontinuation of the manufacture of the drug. Product expected to be available through September 2026.

Desipramine Desipramine Hydrochloride

Tricyclic Antidepressant

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Amphotericin B AmBisome

Lipid-based Polyene Antifungal

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug

Clindamycin and Benzoyl Peroxide Acanya

Lincosamide Antibacterial

Discontinued 2 manufacturers affected

A business decision was made to discontinue manufacture of the product.

Adefovir Dipivoxil

Discontinued Apotex Corp.

Discontinuation of the manufacture of the drug

Esterified Estrogens MENEST

Discontinued Pfizer Inc.

Discontinuation of the manufacture of the drug

Glipizide Glucotrol

Discontinued Pfizer Inc.

Discontinuation of the manufacture of the drug

Amantadine GOCOVRI

Influenza A M2 Protein Inhibitor

Discontinued 2 manufacturers affected

Discontinuation of the manufacture of the drug product

Insulin Aspart .Insulin Aspart Protamine and Insulin Aspart

Discontinued 2 manufacturers affected

Unbranded Insulin Aspart 3 mL FlexPen® will continue to be shipped to wholesalers while supplies last

Shortage data from the FDA Drug Shortage Database. Discontinuation data reflects manufacturer-reported decisions. Drug availability may vary by region and supplier. Source: FDA Drug Shortages.